Multiple organ failure. Pathophysiology and potential future therapy (Q35701721)

9 August 2017

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title

Multiple organ failure. Pathophysiology and potential future therapy (English)

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9 August 2017

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Deitch EA

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9 August 2017

language of work or name

English

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publication date

1 August 1992

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9 August 2017

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9 August 2017

volume

216

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9 August 2017

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9 August 2017

page(s)

117-134

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Bacterial translocation of the gut flora

9 August 2017

cites work

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12 December 2020

Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever

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12 December 2020

Evaluation of APACHE II for cost containment and quality assurance

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12 December 2020

Increased levels of circulating interleukin 6 in burn patients

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Irreversibility in hemorrhagic shock is caused by sepsis

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12 December 2020

Plasma tumor necrosis factor levels in patients with presumed sepsis. Results in those treated with antilipid A antibody vs placebo

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12 December 2020

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome

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12 December 2020

Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans

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12 December 2020

Detection of circulating tumor necrosis factor after endotoxin administration.

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12 December 2020

Nosocomial Pneumonia in Intubated Patients Given Sucralfate as Compared with Antacids or Histamine Type 2 Blockers

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12 December 2020

Early versus delayed stabilization of femoral fractures. A prospective randomized study

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12 December 2020

Oxygen-derived radicals: a link between reperfusion injury and inflammation

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12 December 2020

The gut origin septic states in blunt multiple trauma (ISS = 40) in the ICU.

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12 December 2020

Alteration of monocyte function following major injury

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12 December 2020

Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura

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12 December 2020

Enteral nutrition does not prevent multiple organ failure syndrome (MOFS) after sepsis

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12 December 2020

A single dose of endotoxin increases intestinal permeability in healthy humans

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12 December 2020

Circulating interleukin-1 beta in patients with Kawasaki disease

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12 December 2020

A monoclonal antibody to the adherence-promoting leukocyte glycoprotein, CD18, reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits

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12 December 2020

Causes of mortality in patients with the adult respiratory distress syndrome

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12 December 2020

Multiple-organ failure. Generalized autodestructive inflammation?

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12 December 2020

Acute respiratory distress in adults

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12 December 2020

Alterations in cellular membrane function during hemorrhagic shock in primates

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12 December 2020

Pathophysiology of the respiratory distress syndrome

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12 December 2020

Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal

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12 December 2020

Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme

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12 December 2020

Enteral and parenteral feeding influences mortality after hemoglobin-E. coli peritonitis in normal rats

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12 December 2020

The effect of selective decontamination of the digestive tract on colonisation and infection rate in multiple trauma patients

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12 December 2020

Re-operation for intra-abdominal sepsis. Indications and results in modern critical care setting

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12 December 2020

The efficacy of central venous and pulmonary artery catheters and therapy based upon them in reducing mortality and morbidity

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12 December 2020

Serum cachectin/tumor necrosis factor in critically ill patients with burns correlates with infection and mortality

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12 December 2020

Differential effects of gut hormones on pancreatic and intestinal growth during administration of an elemental diet

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12 December 2020

The role of intestinal barrier failure and bacterial translocation in the development of systemic infection and multiple organ failure

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12 December 2020

Warner-Lambert/Parke-Davis award lecture. Cytokine-mediated activation of vascular endothelium. Physiology and pathology

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12 December 2020

The influence of fibronectin administration on the incidence of sepsis and septic mortality in severely injured patients. The Medical College of Georgia Fibronectin Research Group

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12 December 2020

The effect of anti-intercellular adhesion molecule-1 on phorbol-ester-induced rabbit lung inflammation

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12 December 2020

Inhibition of endotoxin-induced bacterial translocation in mice

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12 December 2020

Clinical experience with prophylactic antibiotic bowel suppression in burn patients

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12 December 2020

Multiple organ failure

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12 December 2020

Remote organ failure: a valid sign of occult intra-abdominal infection

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12 December 2020

Cytokines and endothelial cell biology

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12 December 2020

Nutrient modulation of inflammatory and immune function

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12 December 2020

Tumor necrosis factor (cachectin) in the biology of septic shock syndrome

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12 December 2020

Let's agree on terminology: definitions of sepsis

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12 December 2020

A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice

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12 December 2020

Increased expression of the interleukin 1 receptor on blood neutrophils of humans with the sepsis syndrome

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12 December 2020

Effects of Granulocyte-Macrophage Colony-Stimulating Factor in Burn Patients

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12 December 2020

A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group

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12 December 2020

Catabolic illness. Strategies for enhancing recovery

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12 December 2020

Effect of ibuprofen in patients with severe sepsis: a randomized, double-blind, multicenter study. The Ibuprofen Study Group

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12 December 2020

Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings

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12 December 2020

TEN versus TPN following major abdominal trauma--reduced septic morbidity

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12 December 2020

Multiple forms of IFN-beta 2/IL-6 in serum and body fluids during acute bacterial infection.

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12 December 2020

The effects of tumor necrosis factor and their selective inhibition by ibuprofen

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12 December 2020

Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group

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12 December 2020

Prevention and treatment of endotoxin and sepsis lethality with recombinant human tumor necrosis factor.

1 reference

12 December 2020

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12 December 2020

Plasma tumor necrosis factor and mortality in critically ill septic patients

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12 December 2020

Genetic susceptibility to mucosal damage leads to bacterial translocation in a murine burn model.

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12 December 2020

The serum interleukin 6 response to elective surgery

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12 December 2020

Increased plasma levels of interleukin-6 in sepsis

1 reference

12 December 2020

Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia

1 reference

12 December 2020

Naloxone versus placebo in treatment of septic shock

1 reference

12 December 2020

Association between tumour necrosis factor in serum and fatal outcome in patients with meningococcal disease

1 reference

12 December 2020

The role of intestinal flora on the interactions between nonparenchymal cells and hepatocytes in coculture

1 reference

12 December 2020

A single dose of endotoxin activates neutrophils without activating complement

1 reference

12 December 2020

Raised serum levels of cachectin/tumor necrosis factor alpha in renal allograft rejection

1 reference

12 December 2020

Serial quantitation of endotoxemia and bacteremia during therapy for gram-negative bacterial sepsis

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12 December 2020

Endotoxemia and bacteremia during hemorrhagic shock. The link between trauma and sepsis?

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12 December 2020

Hemorrhagic shock-induced bacterial translocation is reduced by xanthine oxidase inhibition or inactivation

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12 December 2020

Hypermetabolism, organ failure, and metabolic support

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12 December 2020

Clinical analysis of multiple organ failure in burned patients

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12 December 2020

Incidence of necrotizing pancreatitis and factors related to mortality.

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12 December 2020

Non-directed relaparotomy for intra-abdominal sepsis. A futile procedure

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12 December 2020

Effective organ blood flow and bioenergy status in murine peritonitis

1 reference

12 December 2020

Effect of oral antibiotics and bacterial overgrowth on the translocation of the GI tract microflora in burned rats

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12 December 2020

Glutamine metabolism by the intestinal tract

1 reference

12 December 2020

Incidence of adult respiratory distress syndrome in patients with multiple musculoskeletal injuries: effect of early operative stabilization of fractures.

1 reference

12 December 2020

Blunt multiple trauma (ISS 36), femur traction, and the pulmonary failure-septic state

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12 December 2020

Prognosis in acute organ-system failure.

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12 December 2020

Risk factors for multiorgan failure: a case-control study.

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12 December 2020

Bacterial translocation induces procoagulant activity in tissue macrophages. A potential mechanism for end-organ dysfunction

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12 December 2020

Experimental models of pathologic oxygen supply dependency

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12 December 2020

Pharmacologic approach to tissue injury mediated by free radicals and other reactive oxygen metabolites

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12 December 2020

Interleukin-6 and its relation to the humoral immune response and clinical parameters in burned patients

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12 December 2020

The biologic characteristics of cytokines and their implication in surgical injury

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12 December 2020

Intestinal permeability is increased in burn patients shortly after injury

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12 December 2020

Food without fiber promotes bacterial translocation from the gut.

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12 December 2020

Survival of primates in LD100 septic shock following therapy with antibody to tumor necrosis factor (TNF alpha).

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12 December 2020

Leukocyte adhesion to endothelium in inflammation

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12 December 2020

Membrane proteins involved in phagocyte adherence to endothelium

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12 December 2020

The process of microbial translocation

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12 December 2020

Clinical trials of selective decontamination of the digestive tract: review

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12 December 2020

Interleukin 1 receptor antagonist. A new member of the interleukin 1 family

1 reference

12 December 2020

“Sepsis”–Clarity of existing terminology ... or more confusion?

1 reference

12 December 2020

Immediate enteral feeding in burn patients is safe and effective

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12 December 2020

Sequential system failure after rupture of abdominal aortic aneurysms: an unsolved problem in postoperative care

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12 December 2020

Colonization resistance of the digestive tract in conventional and antibiotic-treated mice

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12 December 2020

Monoclonal antibody to TNF in severe septic shock

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12 December 2020

Inhibition of cyclo-oxygenase attenuates the metabolic response to endotoxin in humans

1 reference

12 December 2020

Oxygen-derived free radicals in postischemic tissue injury

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12 December 2020

The gut: a central organ after surgical stress

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12 December 2020

Whole-body inflammation in trauma patients. An autopsy study

1 reference

12 December 2020

Cytokine appearance in human endotoxemia and primate bacteremia

1 reference

12 December 2020

Interferon-gamma restores immune competence after hemorrhagic shock

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12 December 2020

Combined effects of glutamine and epidermal growth factor on the rat intestine

1 reference

12 December 2020

Tumor necrosis factor and the acute metabolic response to tissue injury in man

1 reference

12 December 2020

Increased intestinal permeability associated with infection in burn patients

1 reference

12 December 2020

Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients.

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12 December 2020

Analysis of multiple organ system failure in trauma and nontrauma patients

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12 December 2020

Use of scoring systems to assess patients with surgical sepsis

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12 December 2020

Interleukin 6 (IL-6) in serum and urine of renal transplant recipients

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12 December 2020

Posttraumatic multisystem organ failure

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12 December 2020

The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients

1 reference

12 December 2020

A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock

1 reference

12 December 2020

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1 reference

12 December 2020

Hypothesis: sepsis, multiple systems organ failure, and the macrophage

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12 December 2020

Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor

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12 December 2020

Granulocytes and no-reflow phenomenon in irreversible hemorrhagic shock

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12 December 2020

Intestinal bacteria translocate into experimental intra-abdominal abscesses

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12 December 2020

Both inflammatory and endocrine mediators stimulate host responses to sepsis

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12 December 2020

Endotoxins and disease mechanisms

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12 December 2020

The enhancement of inflammatory injury

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12 December 2020

Role of neutrophils in ischemia-reperfusion-induced microvascular injury

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12 December 2020

Stimulating effect of bombesin on the growth of gastrointestinal tract and pancreas in suckling rats

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12 December 2020

Effects of intraluminal infusion of short-chain fatty acids on the healing of colonic anastomosis in the rat

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12 December 2020

Oxygen delivery and consumption in patients with hyperdynamic septic shock

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12 December 2020

Dependence of oxygen consumption on cardiac output in sepsis

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12 December 2020

Killed Escherichia coli stimulates macrophage-mediated alterations in hepatocellular function during in vitro coculture: a mechanism of altered liver function in sepsis

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12 December 2020

Verapamil improves cardiac function and increases survival in canine E. coli endotoxin shock.

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12 December 2020

Does drainage of intraabdominal pus reverse multiple organ failure?

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12 December 2020

The influence of sepsis and multisystem and organ failure on mortality in the surgical intensive care unit

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12 December 2020

Enterococcal bacteremia: clinical implications and determinants of death

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12 December 2020

Endotoxaemia in septic shock: clinical and post mortem correlations

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12 December 2020

Multiple system organ failure. The role of uncontrolled infection

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12 December 2020

Kinetics of endotoxin release during antibiotic therapy for experimental gram-negative bacterial sepsis

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12 December 2020

Mechanism of prevention of postburn hypermetabolism and catabolism by early enteral feeding

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12 December 2020

Multiple organ failure in polytrauma patients

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12 December 2020

Early osteosynthesis and prophylactic mechanical ventilation in the multitrauma patient

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12 December 2020

The natural history of major burns with multiple subsystem failure

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12 December 2020

Beneficial effects of aggressive protein feeding in severely burned children

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12 December 2020

Translocation of Certain Indigenous Bacteria from the Gastrointestinal Tract to the Mesenteric Lymph Nodes and Other Organs in a Gnotobiotic Mouse Model

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12 December 2020

Immune Interferon in the Circulation of Patients with Autoimmune Disease

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12 December 2020

Multiple, progressive, or sequential systems failure. A syndrome of the 1970s

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12 December 2020

Cytokines: coordinators of immune and inflammatory responses

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12 December 2020

Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats

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12 December 2020

Studies of the route, magnitude, and time course of bacterial translocation in a model of systemic inflammation

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12 December 2020

Immunomodulatory therapy with thymopentin and indomethacin. Successful restoration of interleukin-2 synthesis in patients undergoing major surgery.

1 reference

12 December 2020

Inhibition of CD18-dependent neutrophil adherence reduces organ injury after hemorrhagic shock in primates.

1 reference

12 December 2020

Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group

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12 December 2020

Gut bacterial translocation via the portal vein: a clinical perspective with major torso trauma.

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12 December 2020

Human recombinant interleukin-1 alpha protection against the lethality of endotoxin and experimental sepsis in mice.

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12 December 2020

Definitions of sepsis--have we reached a consensus?

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12 December 2020

Regulatory functions of the vascular endothelium

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12 December 2020

Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia.

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12 December 2020

Elevated circulating levels of tumor necrosis factor in severe chronic heart failure

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12 December 2020

The role of endothelial cells in inflammation

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12 December 2020

10.1097/00000658-199208000-00002

Identifiers

DOI

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National Center for Biotechnology Information

9 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1503516

3 October 2022

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