Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env. (Q35641498)

9 August 2017

title

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env. (English)

1 reference

9 August 2017

John R Mascola

1 reference

9 August 2017

Jason Gorman

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Peter D Kwong

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9 August 2017

Mallika Sastry

1 reference

9 August 2017

Guillaume Stewart-Jones

series ordinal

object named as

Guillaume B E Stewart-Jones

1 reference

9 August 2017

Adrian B McDermott

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9 August 2017

M Gordon Joyce

1 reference

9 August 2017

Ivelin S Georgiev

1 reference

9 August 2017

Sandeep Narpala

1 reference

9 August 2017

Joseph Van Galen

1 reference

9 August 2017

Rita E Chen

1 reference

9 August 2017

Yongping Yang

1 reference

9 August 2017

Aliaksandr Druz

1 reference

9 August 2017

Ulrich Baxa

1 reference

9 August 2017

Marie Pancera

1 reference

9 August 2017

Adam Harned

1 reference

9 August 2017

Arne Schön

1 reference

9 August 2017

Ernesto Freire

1 reference

9 August 2017

Baoshan Zhang

1 reference

9 August 2017

Christopher R Lees

1 reference

9 August 2017

Gwo-Yu Chuang

series ordinal

1 reference

9 August 2017

Cheng Cheng

series ordinal

1 reference

9 August 2017

language of work or name

English

0 references

publication date

4 March 2015

1 reference

9 August 2017

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

5318-5329

1 reference

Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties

9 August 2017

cites work

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Stable, uncleaved HIV-1 envelope glycoprotein gp140 forms a tightly folded trimer with a native-like structure

12 July 2018

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

12 July 2018

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12 July 2018

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12 July 2018

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Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

12 July 2018

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Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

12 July 2018

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Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

12 July 2018

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Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

12 July 2018

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12 July 2018

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

12 July 2018

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12 July 2018

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Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

12 July 2018

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

12 July 2018

1 reference

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A global approach to HIV-1 vaccine development

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Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

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Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

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Proteolytic processing of the human immunodeficiency virus envelope glycoprotein precursor decreases conformational flexibility

12 July 2018

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12 July 2018

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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

12 July 2018

1 reference

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HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

12 July 2018

1 reference

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HIV-1 virus-like particles bearing pure env trimers expose neutralizing epitopes but occlude nonneutralizing epitopes

12 July 2018

1 reference

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Broad neutralization coverage of HIV by multiple highly potent antibodies

12 July 2018

1 reference

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

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Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

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12 July 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment.

25 September 2018

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Conserved structures exposed in HIV-1 envelope glycoproteins stabilized by flexible linkers as potent entry inhibitors and potential immunogens

25 September 2018

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A ligand-receptor fusion of growth hormone forms a dimer and is a potent long-acting agonist

25 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25740988

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.03451-14

1 reference

9 August 2017

1 reference

9 August 2017

1 reference