A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation. (Q35627696)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143885%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation (English)

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17 January 2020

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17 January 2020

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17 January 2020

1 reference

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17 January 2020

Bart A Westerman

1 reference

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17 January 2020

A Koen Braat

1 reference

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17 January 2020

Nicole Taub

1 reference

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17 January 2020

Marko Potman

1 reference

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17 January 2020

Joseph H A Vissers

1 reference

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17 January 2020

Marleen Blom

1 reference

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17 January 2020

Els Verhoeven

1 reference

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17 January 2020

Hans Stoop

1 reference

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17 January 2020

Ad Gillis

1 reference

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17 January 2020

Wouter Nijkamp

1 reference

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17 January 2020

Roderick Beijersbergen

1 reference

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17 January 2020

Maarten van Lohuizen

1 reference

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17 January 2020

language of work or name

English

0 references

publication date

5 December 2011

1 reference

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Journal of Experimental Medicine

17 January 2020

published in

1 reference

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17 January 2020

volume

208

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17 January 2020

issue

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17 January 2020

page(s)

2675-2689

1 reference

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Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.

17 January 2020

cites work

1 reference

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Retinoic acid orchestrates fibroblast growth factor signalling to drive embryonic stem cell differentiation

12 July 2018

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Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration

12 July 2018

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Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation

12 July 2018

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A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

12 July 2018

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ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome

12 July 2018

1 reference

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The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.

12 July 2018

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Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells

12 July 2018

1 reference

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NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs

12 July 2018

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The ground state of embryonic stem cell self-renewal

12 July 2018

1 reference

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Pluripotency and nuclear reprogramming

12 July 2018

1 reference

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An extended transcriptional network for pluripotency of embryonic stem cells

12 July 2018

1 reference

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FOXL2 and SOX9 as parameters of female and male gonadal differentiation in patients with various forms of disorders of sex development (DSD).

12 July 2018

1 reference

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Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications

12 July 2018

1 reference

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Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion

12 July 2018

1 reference

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

12 July 2018

1 reference

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Derivation of pluripotent epiblast stem cells from mammalian embryos

12 July 2018

1 reference

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New cell lines from mouse epiblast share defining features with human embryonic stem cells

12 July 2018

1 reference

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Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets

12 July 2018

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Generation of germline-competent induced pluripotent stem cells

12 July 2018

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Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.

12 July 2018

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Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal

12 July 2018

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Scaffold proteins of MAP-kinase modules.

12 July 2018

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MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal

12 July 2018

1 reference

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Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling

12 July 2018

1 reference

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p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

12 July 2018

1 reference

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A protein interaction network for pluripotency of embryonic stem cells

12 July 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

12 July 2018

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Feeder-independent culture of human embryonic stem cells

12 July 2018

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Dissecting self-renewal in stem cells with RNA interference

12 July 2018

1 reference

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The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

12 July 2018

1 reference

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The NuRD component Mbd3 is required for pluripotency of embryonic stem cells

12 July 2018

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Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

12 July 2018

1 reference

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Core transcriptional regulatory circuitry in human embryonic stem cells

12 July 2018

1 reference

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Transcriptional regulation of nanog by OCT4 and SOX2.

12 July 2018

1 reference

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Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

12 July 2018

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Testicular germ-cell tumours in a broader perspective.

12 July 2018

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Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4

12 July 2018

1 reference

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BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways

12 July 2018

1 reference

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BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

12 July 2018

1 reference

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Role of ERas in promoting tumour-like properties in mouse embryonic stem cells

12 July 2018

1 reference

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Ras proteins: different signals from different locations

12 July 2018

1 reference

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POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis

12 July 2018

1 reference

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From teratocarcinomas to embryonic stem cells

12 July 2018

1 reference

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Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).

12 July 2018

1 reference

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A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment

12 July 2018

1 reference

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Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

12 July 2018

1 reference

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An Eph receptor regulates integrin activity through R-Ras

12 July 2018

1 reference

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Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

12 July 2018

1 reference

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Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

12 July 2018

1 reference

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Generation of purified neural precursors from embryonic stem cells by lineage selection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Maintenance of an extrachromosomal plasmid vector in mouse embryonic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

12 July 2018

1 reference

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Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

12 July 2018

1 reference

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An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo

12 July 2018

1 reference

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Differentiation of aggregated murine P19 embryonal carcinoma cells is induced by a novel visceral endoderm-specific FGF-like factor and inhibited by activin A.

12 July 2018

1 reference

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FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive Streak

12 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102037

Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102037

H-Ras dynamically interacts with recycling endosomes in CHO-K1 cells: involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102037

Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102037

Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity

21 January 2018

1 reference

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Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells

21 January 2018

1 reference

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Differential modification of Ras proteins by ubiquitination

21 January 2018

1 reference

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FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.

21 January 2018

1 reference

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Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102037

Lineage specific differentiation of mouse ES cells: formation and differentiation of early primitive ectoderm-like (EPL) cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244037

Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells

25 September 2018

1 reference

12 December 2020

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

1 reference

12 December 2020

Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors

1 reference

12 December 2020

Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny

1 reference

12 December 2020

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20102037

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143885%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143885%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

22143885

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143885%20AND%20SRC:MED&resulttype=core&format=json