Effects of noradrenergic denervation on L-DOPA-induced dyskinesia and its treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats. (Q35624275)

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scientific article published on 25 September 2011

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English	Effects of noradrenergic denervation on L-DOPA-induced dyskinesia and its treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats.	scientific article published on 25 September 2011

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14 February 2020

Effects of noradrenergic denervation on L-DOPA-induced dyskinesia and its treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats (English)

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David Lindenbach

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Christopher J Barnum

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Nirmal Bhide

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Christopher Bishop

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Pharmacology, Biochemistry and Behavior

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14 February 2020

Behavioral and cellular modulation of L-DOPA-induced dyskinesia by beta-adrenoceptor blockade in the 6-hydroxydopamine-lesioned rat.

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Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease

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A comprehensive analysis of the effect of DSP4 on the locus coeruleus noradrenergic system in the rat

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Contribution of the striatum to the effects of 5-HT1A receptor stimulation in L-DOPA-treated hemiparkinsonian rats

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Advances in understanding L-DOPA-induced dyskinesia

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Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice

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Norepinephrine: The redheaded stepchild of Parkinson's disease

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Abnormal involuntary movements (AIMs) following pulsatile dopaminergic stimulation: severe deterioration and morphological correlates following the loss of locus coeruleus neurons.

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Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys

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27 July 2018

The alpha2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances anti-parkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease

1 reference

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Improvement of levodopa-induced dyskinesia by propranolol in Parkinson's disease

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27 July 2018

Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.

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Telencephalic projections from midbrain and isthmal cell groups in the pigeon. I. Locus coeruleus and subcoeruleus

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27 July 2018

Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: a possible role for the locus coeruleus in the progression of Parkinson's disea

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27 July 2018

Effects of locus coeruleus lesions on the release of endogenous dopamine in the rat nucleus accumbens and caudate nucleus as determined by intracerebral microdialysis

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Beta-adrenergic receptor subtypes in the basal ganglia of patients with Huntington's chorea and Parkinson's disease

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27 July 2018

Electrolytic lesions of the locus coeruleus or 6-hydroxydopamine lesions of the medial forebrain bundle protect against excitotoxic damage in rat hippocampus

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27 July 2018

Projections of the locus coeruleus and adjacent pontine tegmentum in the cat

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27 July 2018

Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study

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1 reference

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Alpha2-adrenergic control of dopamine overflow and metabolism in mouse striatum

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Santhera licenses novel dyskinesia therapy to Biovail

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Locus coeruleus lesions potentiate neurotoxic effects of MPTP in dopaminergic neurons of the substantia nigra

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Norepinephrine loss exacerbates methamphetamine-induced striatal dopamine depletion in mice

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Noradrenaline and adrenaline are high affinity agonists at dopamine D4 receptors

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DL-threo-3,4-dihydroxyphenylserine for freezing symptom in parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21978941

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Development of brain beta-adrenergic receptors after neonatal 6-hydroxydopamine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21978941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of subtypes of beta-adrenergic receptors in rat brain following treatment with 6-hydroxydopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21978941

12 December 2020

based on heuristic

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Destruction of norepinephrine terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice reduces locomotor activity induced by L-dopa

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[Analysis of L-threo-3, 4-dihydroxyphenylserine effect on motor and psychological symptoms in Parkinson's disease]

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https://pubmed.ncbi.nlm.nih.gov/21978941

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Identifiers

10.1016/J.PBB.2011.09.009

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978941%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978941%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978941%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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