Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance (Q35608446)

9 August 2017

title

Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance (English)

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9 August 2017

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C R Kahn

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9 August 2017

M. J. Saad

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1331176

14 September 2022

E. Araki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1331176

14 September 2022

M. Miralpeix

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1331176

14 September 2022

P. L. Rothenberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1331176

14 September 2022

M. F. White

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1331176

14 September 2022

language of work or name

English

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publication date

1 November 1992

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full work available at URL

9 August 2017

https://europepmc.org/articles/PMC443244

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1331176

https://europepmc.org/articles/PMC443244?pdf=render

14 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1331176

Journal of Clinical Investigation

14 September 2022

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

1839-1849

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Insulin Receptors and Insulin Resistance

9 August 2017

cites work

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

12 July 2018

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Normal hepatic insulin receptor autophosphorylation in nonketotic diabetes mellitus.

12 July 2018

1 reference

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Molecular association between major histocompatibility complex class I antigens and insulin receptors in mouse liver membranes

12 July 2018

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The glucose transporter in 3T3-L1 adipocytes is phosphorylated in response to phorbol ester but not in response to insulin

12 July 2018

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Brown adipose tissue in lean and obese mice. Insulin-receptor binding and tyrosine kinase activity

12 July 2018

1 reference

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Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

12 July 2018

1 reference

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Intact adipocyte insulin-receptor phosphorylation and in vitro tyrosine kinase activity in animal models of insulin resistance

12 July 2018

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Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity

12 July 2018

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The insulin receptor and the molecular mechanism of insulin action

12 July 2018

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Insulin receptor tyrosine kinase activity is unaltered in ob/ob and db/db mouse skeletal muscle membranes

12 July 2018

1 reference

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Differential sensitivity of two functions of the insulin receptor to the associated proteolysis: kinase action and hormone binding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443244

Insulin receptor kinase activity in rat liver. Regulation by fasting and high carbohydrate feeding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443244

Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation

12 July 2018

1 reference

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Insulin and insulin-like growth factor-I stimulate a common endogenous phosphoprotein substrate (pp185) in intact neuroblastoma cells

12 July 2018

1 reference

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Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443244

Hepatic phosphotyrosine phosphatase activity and its alterations in diabetic rats

12 July 2018

1 reference

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Dexamethasone-induced changes in phosphorylation of the insulin and epidermal growth factor receptors and their substrates in intact rat hepatocytes.

12 July 2018

1 reference

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12 July 2018

1 reference

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Autophosphorylation and kinase activity of insulin receptor in diabetic rats.

12 July 2018

1 reference

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Purification of the catalytically active phosphorylated form of insulin receptor kinase by affinity chromatography with O-phosphotyrosyl-binding antibodies.

12 July 2018

1 reference

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Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects

12 July 2018

1 reference

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Insulin binding and receptor tyrosine kinase activity in rat liver and skeletal muscle: effect of starvation

12 July 2018

1 reference

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

12 July 2018

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

12 July 2018

1 reference

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Effect of Fasting on Insulin Binding to Hepatocytes and Liver Plasma Membranes from Rats*

12 July 2018

1 reference

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

12 July 2018

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Insulin binding to liver plasm membranes in the obese hyperglycemic (ob/ob) mouse. Demonstration of a decreased number of functionally normal receptors

12 July 2018

1 reference

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Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats.

12 July 2018

1 reference

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Divergent molecular mechanisms for insulin-resistant glucose transport in muscle and adipose cells in vivo.

25 September 2018

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Immunological detection of phosphotyrosine-containing proteins in rat livers after insulin injection

25 September 2018

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12 December 2020

Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase

1 reference

12 December 2020

Effects of hypercortisolemia and diabetes on skeletal muscle insulin receptor function in vitro and in vivo

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12 December 2020

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin

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12 December 2020

Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor

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12 December 2020

Diabetes-Associated Impairment of Hepatic Insulin Receptor Tyrosine Kinase Activity: A Study of Mechanisms*

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12 December 2020

Phospholipid activation of the insulin receptor kinase: regulation by phosphatidylinositol

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12 December 2020

Insulin-induced tyrosine-phosphorylation in intact rat adipocytes

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12 December 2020

Insulin resistance is a prominent feature of insulin-dependent diabetes

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12 December 2020

Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

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12 December 2020

Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell

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12 December 2020

Characterization of an endogenous substrate of the insulin receptor in cultured cells

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12 December 2020

Identifiers

DOI

10.1172/JCI116060

1 reference

9 August 2017

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9 August 2017

1 reference