HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase (Q35267783)

7 August 2017

title

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase (English)

1 reference

7 August 2017

Espeseth AS

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7 August 2017

Felock P

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7 August 2017

Wolfe A

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7 August 2017

Witmer M

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7 August 2017

Grobler J

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7 August 2017

Anthony N

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7 August 2017

Egbertson M

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7 August 2017

Melamed JY

1 reference

7 August 2017

Young S

1 reference

7 August 2017

Hamill T

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7 August 2017

Cole JL

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7 August 2017

Hazuda DJ

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7 August 2017

language of work or name

English

0 references

publication date

1 October 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

11244-11249

1 reference

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

7 August 2017

cites work

1 reference

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

12 July 2018

1 reference

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Stereospecificity of reactions catalyzed by HIV-1 integrase

12 July 2018

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Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

12 July 2018

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Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant

12 July 2018

1 reference

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Inhibitors of human immunodeficiency virus integrase.

12 July 2018

1 reference

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Crystal structures of catalytic core domains of retroviral integrases and role of divalent cations in enzymatic activity.

12 July 2018

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Discovery and analysis of inhibitors of the human immunodeficiency integrase.

12 July 2018

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The core domain of HIV-1 integrase recognizes key features of its DNA substrates

12 July 2018

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Differential divalent cation requirements uncouple the assembly and catalytic reactions of human immunodeficiency virus type 1 integrase

12 July 2018

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Characterization of feline immunodeficiency virus integrase and analysis of functional domains

12 July 2018

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Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules

12 July 2018

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The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates

12 July 2018

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Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations.

12 July 2018

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Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

12 July 2018

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Complementation between HIV integrase proteins mutated in different domains

12 July 2018

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Substrate features important for recognition and catalysis by human immunodeficiency virus type 1 integrase identified by using novel DNA substrates

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

A novel assay for the DNA strand-transfer reaction of HIV-1 integrase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Characterization of the minimal DNA-binding domain of the HIV integrase protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Substrate specificity of recombinant human immunodeficiency virus integrase protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17185

Scintillation proximity assay

12 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.200139397

Scintillation Proximity Enzyme Assay a Rapid and Novel Assay Technique Applied to HIV Proteinase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11016953

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11016953

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.200139397

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference