IL-15 delays suppression and fails to promote immune reconstitution in virally suppressed chronically SIV-infected macaques. (Q35197395)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

IL-15 delays suppression and fails to promote immune reconstitution in virally suppressed chronically SIV-infected macaques (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Mario Roederer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Francois Villinger

1 reference

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7 February 2020

Enrico Lugli

1 reference

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7 February 2020

Mark G Lewis

series ordinal

1 reference

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7 February 2020

language of work or name

English

0 references

publication date

14 July 2011

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7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

118

1 reference

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7 February 2020

issue

1 reference

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7 February 2020

page(s)

2520-2529

1 reference

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SPICE: exploration and analysis of post-cytometric complex multivariate datasets

7 February 2020

cites work

1 reference

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Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model

13 July 2018

1 reference

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Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

13 July 2018

1 reference

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Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

13 July 2018

1 reference

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Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.

13 July 2018

1 reference

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Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection

13 July 2018

1 reference

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IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment

13 July 2018

1 reference

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IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses

13 July 2018

1 reference

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Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection

13 July 2018

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The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

13 July 2018

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Failure to reconstitute CD4+ T-cells despite suppression of HIV replication under HAART.

13 July 2018

1 reference

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Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge

13 July 2018

1 reference

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IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

13 July 2018

1 reference

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Immunological recovery and antiretroviral therapy in HIV-1 infection

13 July 2018

1 reference

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Interleukin-15 increases effector memory CD8+ t cells and NK Cells in simian immunodeficiency virus-infected macaques

13 July 2018

1 reference

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167360

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167360

IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167360

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167360

Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167360

Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

13 July 2018

1 reference

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The dynamics of CD4+ T-cell depletion in HIV disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167360

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167360

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

13 July 2018

1 reference

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CD4+ T-cell differentiation, regulatory T cells and gag-specific T lymphocytes are unaffected by CD4-guided treatment interruption and therapy resumption

13 July 2018

1 reference

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CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads

26 September 2018

1 reference

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Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

26 September 2018

1 reference

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Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques

26 September 2018

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Highly sensitive SIV plasma viral load assay: practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS.

26 September 2018

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Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

26 September 2018

1 reference

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Immune reconstitution in the sigmoid colon after long-term HIV therapy

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21757617

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21757617

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21757617

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2011-05-351155

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

21757617

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21757617%20AND%20SRC:MED&resulttype=core&format=json