Who's on first in the cellular response to DNA damage? (Q35120155)

6 August 2017

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title

Who's on first in the cellular response to DNA damage? (English)

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6 August 2017

0 references

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30 December 2023

Philip C. Hanawalt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728270

30 December 2023

Susan D. Cline

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728270

30 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12728270

30 December 2023

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

http://www.nature.com/articles/nrm1101.pdf

file format

Portable Document Format

1 reference

http://www.nature.com/articles/nrm1101

30 December 2023

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Nature Reviews Molecular Cell Biology

30 December 2023

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

361-372

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Instability and decay of the primary structure of DNA

6 August 2017

cites work

1 reference

Mammalian DNA single-strand break repair: an X-ra(y)ted affair

31 March 2020

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Partners and pathwaysrepairing a double-strand break.

31 March 2020

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Base excision repair in yeast and mammals

31 March 2020

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31 March 2020

Human DNA repair genes

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Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations

31 March 2020

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Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors

31 March 2020

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Molecular mechanism of nucleotide excision repair.

31 March 2020

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Damage recognition in nucleotide excision repair of DNA.

31 March 2020

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Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis

31 March 2020

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Effect of DNA lesions on transcription elongation

31 March 2020

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Mechanisms of transcription-coupled DNA repair

31 March 2020

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Recognition of DNA alterations by the mismatch repair system

31 March 2020

1 reference

Molecular mechanisms of DNA mismatch repair

31 March 2020

1 reference

Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair

31 March 2020

1 reference

In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair

31 March 2020

1 reference

Strand-specific mismatch repair in mammalian cells

31 March 2020

1 reference

Eukaryotic DNA mismatch repair

31 March 2020

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Reversal of DNA alkylation damage by two human dioxygenases

31 March 2020

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Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

31 March 2020

1 reference

Mammalian DNA repair methyltransferases shield O4MeT from nucleotide excision repair.

31 March 2020

1 reference

Functional nucleotide excision repair is required for the preferential removal of N-ethylpurines from the transcribed strand of the dihydrofolate reductase gene of Chinese hamster ovary cells

31 March 2020

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Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

31 March 2020

1 reference

Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes

31 March 2020

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Enzymatic photoreactivation: 50 years and counting

31 March 2020

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Escherichia coli DNA photolyase stimulates uvrABC excision nuclease in vitro

31 March 2020

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Interactions between yeast photolyase and nucleotide excision repair proteins in Saccharomyces cerevisiae and Escherichia coli

31 March 2020

1 reference

RNA polymerase II transcription inhibits DNA repair by photolyase in the transcribed strand of active yeast genes

31 March 2020

1 reference

Nucleotide excision repair and photolyase preferentially repair the nontranscribed strand of RNA polymerase III-transcribed genes in Saccharomyces cerevisiae

31 March 2020

1 reference

Chromatin structure modulates DNA repair by photolyase in vivo

31 March 2020

1 reference

A damage-responsive DNA binding protein regulates transcription of the yeast DNA repair gene PHR1

31 March 2020

1 reference

TFIIH plays an essential role in RNA polymerase I transcription

31 March 2020

1 reference

Transcription-coupled repair deficiency and mutations in human mismatch repair genes

31 March 2020

1 reference

Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli

31 March 2020

1 reference

Transcription-coupled repair in RNA polymerase I-transcribed genes of yeast

31 March 2020

1 reference

DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner

31 March 2020

1 reference

Nucleotide sequence context effect of a cyclobutane pyrimidine dimer upon RNA polymerase II transcription

31 March 2020

1 reference

Lack of transcription-coupled repair in mammalian ribosomal RNA genes

31 March 2020

1 reference

Lack of gene- and strand-specific DNA repair in RNA polymerase III-transcribed human tRNA genes

31 March 2020

1 reference

Inhibition of RNA polymerase II as a trigger for the p53 response

31 March 2020

1 reference

Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

31 March 2020

1 reference

Replication protein A interactions with DNA. 2. Characterization of double-stranded DNA-binding/helix-destabilization activities and the role of the zinc-finger domain in DNA interactions

31 March 2020

1 reference

Interactions of mammalian proteins with cisplatin-damaged DNA.

31 March 2020

1 reference

Human replication protein A preferentially binds cisplatin-damaged duplex DNA in vitro

31 March 2020

1 reference

Molecular anatomy of the human excision nuclease assembled at sites of DNA damage

31 March 2020

1 reference

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

31 March 2020

1 reference

An affinity of human replication protein A for ultraviolet-damaged DNA.

31 March 2020

1 reference

Replication protein A interactions with DNA. III. Molecular basis of recognition of damaged DNA.

31 March 2020

1 reference

Mechanism of open complex and dual incision formation by human nucleotide excision repair factors

31 March 2020

1 reference

Characterization of reaction intermediates of human excision repair nuclease.

31 March 2020

1 reference

DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair

31 March 2020

1 reference

Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA

31 March 2020

1 reference

Specific binding of human MSH2.MSH6 mismatch-repair protein heterodimers to DNA incorporating thymine- or uracil-containing UV light photoproducts opposite mismatched bases.

31 March 2020

1 reference

MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae

31 March 2020

1 reference

Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct

31 March 2020

1 reference

The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin

31 March 2020

1 reference

Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.

31 March 2020

1 reference

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

31 March 2020

1 reference

Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts

31 March 2020

1 reference

MutS recognition of exocyclic DNA adducts that are endogenous products of lipid oxidation

31 March 2020

1 reference

Repair of propanodeoxyguanosine by nucleotide excision repair in vivo and in vitro

31 March 2020

1 reference

Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6

31 March 2020

1 reference

Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer

31 March 2020

1 reference

Physical interaction between components of DNA mismatch repair and nucleotide excision repair

31 March 2020

1 reference

Recognition of cisplatin adducts by cellular proteins

31 March 2020

1 reference

Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins

31 March 2020

1 reference

Co-crystal structure of TBP recognizing the minor groove of a TATA element

31 March 2020

1 reference

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

31 March 2020

1 reference

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

31 March 2020

1 reference

HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease

31 March 2020

1 reference

Repair of cisplatin--DNA adducts by the mammalian excision nuclease

31 March 2020

1 reference

Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities.

31 March 2020

1 reference

Binding of Ixr1, a yeast HMG-domain protein, to cisplatin-DNA adducts in vitro and in vivo

31 March 2020

1 reference

The HMG-domain protein Ixr1 blocks excision repair of cisplatin-DNA adducts in yeast

31 March 2020

1 reference

Ixr1, a yeast protein that binds to platinated DNA and confers sensitivity to cisplatin

31 March 2020

1 reference

Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro

31 March 2020

1 reference

Nhp6, an HMG1 protein, functions in SNR6 transcription by RNA polymerase III in S. cerevisiae

31 March 2020

1 reference

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box

31 March 2020

1 reference

Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A.

31 March 2020

1 reference

Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor).

31 March 2020

1 reference

Cisplatin inhibits synthesis of ribosomal RNA in vivo

31 March 2020

1 reference

Cisplatin-DNA adducts inhibit ribosomal RNA synthesis by hijacking the transcription factor human upstream binding factor

31 March 2020

1 reference

Kinetic studies of the TATA-binding protein interaction with cisplatin-modified DNA

31 March 2020

1 reference

Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.

31 March 2020

1 reference

UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation

31 March 2020

1 reference

The major chromatin protein histone H1 binds preferentially to cis-platinum-damaged DNA

31 March 2020

1 reference

The Fanconi anaemia/BRCA pathway

31 March 2020

1 reference

Repair of DNA interstrand cross-links

31 March 2020

1 reference

Mice with a targeted disruption of the Fanconi anemia homolog Fanca

31 March 2020

1 reference

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

31 March 2020

1 reference

Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice

31 March 2020

1 reference

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

31 March 2020

1 reference

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

31 March 2020

1 reference

Fanconi anemia, complementation group A, cells are defective in ability to produce incisions at sites of psoralen interstrand cross-links

31 March 2020

1 reference

Human alpha spectrin II and the FANCA, FANCC, and FANCG proteins bind to DNA containing psoralen interstrand cross-links

31 March 2020

1 reference

Human alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complex

31 March 2020

1 reference

Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex

31 March 2020

1 reference

FANCE: the link between Fanconi anaemia complex assembly and activity

31 March 2020

1 reference

FANCD2: a branch-point in DNA damage response?

31 March 2020

1 reference

BRCA1 interacts directly with the Fanconi anemia protein FANCA

31 March 2020

1 reference

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

31 March 2020

1 reference

Cell cycle checkpoint signaling through the ATM and ATR kinases

31 March 2020

1 reference

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

31 March 2020

1 reference

Preferential binding of ATR protein to UV-damaged DNA.

31 March 2020

1 reference

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint

31 March 2020

1 reference

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

31 March 2020

1 reference

Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice

31 March 2020

1 reference

Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

31 March 2020

1 reference

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

31 March 2020

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Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

31 March 2020

1 reference

The response of eukaryotic topoisomerases to DNA damage

31 March 2020

1 reference

Benzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages

31 March 2020

1 reference

Induction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells

31 March 2020

1 reference

Characterization of the interaction between topoisomerase II and DNA by transcriptional footprinting

31 March 2020

1 reference

Overexpression of type I topoisomerases sensitizes yeast cells to DNA damage

31 March 2020

1 reference

Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint

31 March 2020

1 reference

Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress.

31 March 2020

1 reference

Large-scale fragmentation of mammalian DNA in the course of apoptosis proceeds via excision of chromosomal DNA loops and their oligomers

31 March 2020

1 reference

DNA abasic lesions in a different light: solution structure of an endogenous topoisomerase II poison.

31 March 2020

1 reference

Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions

31 March 2020

1 reference

Base excision repair intermediates as topoisomerase II poisons

31 March 2020

1 reference

Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

31 March 2020

1 reference

Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine

31 March 2020

1 reference

Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage

31 March 2020

1 reference

Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenine

31 March 2020

1 reference

Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects

31 March 2020

1 reference

Stimulated activity of human topoisomerases IIalpha and IIbeta on RNA-containing substrates

31 March 2020

1 reference

Position-specific effect of ribonucleotides on the cleavage activity of human topoisomerase II.

31 March 2020

1 reference

Cytosine arabinoside lesions are position-specific topoisomerase II poisons and stimulate DNA cleavage mediated by the human type II enzymes

31 March 2020

1 reference

31 March 2020

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30 December 2023

Identifiers

DOI

10.1038/NRM1101

1 reference

Dimensions Publication ID

6 August 2017

1005366402

0 references

1 reference