Transcriptional repression mediated by the p53 tumour suppressor (Q35116644)

6 August 2017

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title

Transcriptional repression mediated by the p53 tumour suppressor (English)

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6 August 2017

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https://api.crossref.org/works/10.1038/SJ.CDD.4401191

28 December 2023

Ho J

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6 August 2017

Benchimol S

series ordinal

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6 August 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12719716

28 December 2023

publication date

1 April 2003

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full work available at URL

6 August 2017

http://www.nature.com/articles/4401191

1 reference

DOI

https://api.crossref.org/works/10.1038/SJ.CDD.4401191

http://www.nature.com/articles/4401191.pdf

28 December 2023

file format

Portable Document Format

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DOI

https://api.crossref.org/works/10.1038/SJ.CDD.4401191

Cell Death & Differentiation

28 December 2023

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

404-408

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Transcriptional activation by p53 correlates with suppression of growth but not transformation.

6 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Sequence-specific transcriptional activation is essential for growth suppression by p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Identification of a novel p53 functional domain that is necessary for mediating apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

A model for p53-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Wild-type p53 can down-modulate the activity of various promoters

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Wild-type p53 binds to the TATA-binding protein and represses transcription

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Bcl-2 blocks p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Hepatocyte nuclear factor 3 relieves chromatin-mediated repression of the alpha-fetoprotein gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Divergent regulation of the growth-promoting gene IEX-1 by the p53 tumor suppressor and Sp1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Negative regulation of bcl-2 expression by p53 in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Modulation of the transcriptional activity of thyroid hormone receptors by the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Transcriptional repression by p53 through direct binding to a novel DNA element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 represses CAAT enhancer-binding protein (C/EBP)-dependent transcription of the albumin gene. A molecular mechanism involved in viral liver infection with implications for hepatocarcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Inhibition of cyclooxygenase-2 gene expression by p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Dissecting the regulatory circuitry of a eukaryotic genome

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

RB and hbrm cooperate to repress the activation functions of E2F1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Repression of BRCA1 through a feedback loop involving p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Downmodulation of bFGF-binding protein expression following restoration of p53 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Regulation of transcription of the human presenilin-1 gene by ets transcription factors and the p53 protooncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

p53 regulates a G2 checkpoint through cyclin B1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401191

7 January 2021

Identifiers

DOI

1 reference

6 August 2017

1 reference