Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease (Q35103526)

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English	Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease (English)

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Europe PubMed Central

PubMed publication ID

6 August 2017

Alzheimer's disease

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John Q. Trojanowski

7

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John Q Trojanowski

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Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Syaun Sung

1

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6 August 2017

Hengxuan Yang

2

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6 August 2017

Kunihiro Uryu

3

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6 August 2017

Edward B Lee

4

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6 August 2017

Lei Zhao

5

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6 August 2017

Diana Shineman

6

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6 August 2017

Virginia M-Y Lee

8

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6 August 2017

Domenico Praticò

9

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6 August 2017

language of work or name

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publication date

1 December 2004

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6 August 2017

The American Journal of Pathology

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6 August 2017

165

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Europe PubMed Central

PubMed publication ID

6 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2197-2206

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Europe PubMed Central

PubMed publication ID

6 August 2017

Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures.

1 reference

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9 July 2018

Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß 42 by Inhibiting Rho

1 reference

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9 July 2018

Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity

1 reference

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9 July 2018

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

1 reference

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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

1 reference

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9 July 2018

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

1 reference

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9 July 2018

The isoprostanes in biology and medicine

1 reference

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Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.

1 reference

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Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals

1 reference

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Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice

1 reference

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Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

1 reference

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Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis

1 reference

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9 July 2018

Cyclooxygenases: structural, cellular, and molecular biology

1 reference

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Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

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9 July 2018

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

1 reference

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9 July 2018

PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein

1 reference

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9 July 2018

The in vivo assessment of nimesulide cyclooxygenase-2 selectivity

1 reference

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9 July 2018

Inhibition of brain cyclooxygenase-2 activity and the antipyretic action of nimesulide

1 reference

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Risk of Alzheimer's disease and duration of NSAID use.

1 reference

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9 July 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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9 July 2018

Effects of nonsteroidal antiinflammatory drugs on oxidative pathways in A/J mice

1 reference

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Epitopes that span the tau molecule are shared with paired helical filaments.

1 reference

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Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study

1 reference

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27 September 2018

Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618710

27 September 2018

Effects of nonsteroidal anti-inflammatory drugs on transforming growth factor-beta expression and bioactivity in rat osteoblast-enriched culture

1 reference

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Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

1 reference

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Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice

1 reference

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Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons

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Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology.

1 reference

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Presenilins are not required for A beta 42 production in the early secretory pathway

1 reference

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Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

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Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis.

1 reference

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A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

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1 reference

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27 September 2018

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

1 reference

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Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons.

1 reference

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Decreased expression of prostaglandin G/H synthase-2 (PGHS-2) in Alzheimer's disease brain.

1 reference

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1 reference

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Comparative analgesic activity of nimesulide and diclofenac by intramuscular route: correlation with pharmacokinetic profile of nimesulide

1 reference

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7 January 2021

Direct analysis of indomethacin in rat plasma using a column-switching high-performance liquid chromatographic system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15579461

12 December 2020

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10.1016/S0002-9440(10)63269-5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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