Induced pluripotent stem cells: opportunities and challenges (Q35088515)

6 August 2017

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title

Induced pluripotent stem cells: opportunities and challenges. (English)

1 reference

6 August 2017

Shinya Yamanaka

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6 August 2017

Keisuke Okita

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6 August 2017

language of work or name

English

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publication date

1 August 2011

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Philosophical Transactions of the Royal Society B

6 August 2017

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inferred from page(s)

published in

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6 August 2017

volume

366

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6 August 2017

issue

1575

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6 August 2017

page(s)

2198-2207

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Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

6 August 2017

cites work

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Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine

8 July 2018

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Promotion of direct reprogramming by transformation-deficient Myc.

8 July 2018

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

8 July 2018

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Epigenetic memory in induced pluripotent stem cells

8 July 2018

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Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

8 July 2018

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A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

8 July 2018

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Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury

8 July 2018

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Dental pulp cells for induced pluripotent stem cell banking.

8 July 2018

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Generation of human induced pluripotent stem cells from oral mucosa.

8 July 2018

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Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

8 July 2018

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A nonviral minicircle vector for deriving human iPS cells

8 July 2018

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Tbx3 improves the germ-line competency of induced pluripotent stem cells

8 July 2018

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Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

8 July 2018

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Reprogramming towards pluripotency requires AID-dependent DNA demethylation

8 July 2018

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Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells

8 July 2018

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Direct cell reprogramming is a stochastic process amenable to acceleration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

8 July 2018

1 reference

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Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

8 July 2018

1 reference

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Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

8 July 2018

1 reference

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Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells

8 July 2018

1 reference

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Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2.

8 July 2018

1 reference

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TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells

8 July 2018

1 reference

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Variation in the safety of induced pluripotent stem cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

8 July 2018

1 reference

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Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

8 July 2018

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

8 July 2018

1 reference

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Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

8 July 2018

1 reference

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Generation of induced pluripotent stem cell lines from Tibetan miniature pig.

8 July 2018

1 reference

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Embryonic stem cell-specific microRNAs promote induced pluripotency

8 July 2018

1 reference

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Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

8 July 2018

1 reference

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Human induced pluripotent stem cells free of vector and transgene sequences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Generation of induced pluripotent stem cells from human blood

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Generation of mouse induced pluripotent stem cells without viral vectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Wnt signaling promotes reprogramming of somatic cells to pluripotency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Marked differences in differentiation propensity among human embryonic stem cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

let-7 regulates self renewal and tumorigenicity of breast cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Induced pluripotent stem cell lines derived from human somatic cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

UTF1 is a chromatin-associated protein involved in ES cell differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Derivation of pluripotent epiblast stem cells from mammalian embryos

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

New cell lines from mouse epiblast share defining features with human embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Generation of germline-competent induced pluripotent stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Dissecting self-renewal in stem cells with RNA interference

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Low O2 tensions and the prevention of differentiation of hES cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Viable offspring derived from fetal and adult mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Efficient selection for high-expression transfectants with a novel eukaryotic vector

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Lab-specific gene expression signatures in pluripotent stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Conversion of ancestral fibroblasts to induced pluripotent stem cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Characterization of human UTF1, a chromatin-associated protein with repressor activity expressed in pluripotent cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130417

Patient-specific pluripotent stem cells become even more accessible

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSTB.2011.0016

Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSTB.2011.0016

Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors

21 January 2018

1 reference

12 December 2020

Generation of induced pluripotent stem cell lines from adult rat cells

1 reference

12 December 2020

Hypoxia enhances the generation of induced pluripotent stem cells

1 reference

12 December 2020

Generation of canine induced pluripotent stem cells by retroviral transduction and chemical inhibitors

1 reference

12 December 2020

Identifiers

DOI

10.1098/RSTB.2011.0016

1 reference

6 August 2017

1 reference

6 August 2017

1 reference