CD4+ T cells, including Th17 and cycling subsets, are intact in the gut mucosa of HIV-1-infected long-term nonprogressors (Q35076969)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

CD4+ T cells, including Th17 and cycling subsets, are intact in the gut mucosa of HIV-1-infected long-term nonprogressors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Leonid B Margolis

1 reference

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27 January 2020

Angélique Biancotto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Jamieson H Greenwald

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Philip I Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Sarah W Read

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Michael A Yao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Jessica N Hodge

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

William L Thompson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Stephen B Kovacs

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Cheryl L Chairez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Stephen A Migueles

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Joseph A Kovacs

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

language of work or name

English

0 references

publication date

6 April 2011

1 reference

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27 January 2020

1 reference

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27 January 2020

volume

1 reference

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27 January 2020

issue

1 reference

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27 January 2020

page(s)

5880-5888

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals

27 January 2020

cites work

1 reference

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Interferon-alpha drives monocyte gene expression in chronic unsuppressed HIV-1 infection

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Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection

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8 July 2018

1 reference

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Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels

8 July 2018

1 reference

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Monitoring alpha4beta7 integrin expression on circulating CD4+ T cells as a surrogate marker for tracking intestinal CD4+ T-cell loss in SIV infection.

8 July 2018

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8 July 2018

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Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.

8 July 2018

1 reference

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Immunopathogenesis of asymptomatic chronic HIV Infection: the calm before the storm

8 July 2018

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Evidence for translocation of microbial products in patients with idiopathic CD4 lymphocytopenia.

8 July 2018

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Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection

8 July 2018

1 reference

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Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control

8 July 2018

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Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

8 July 2018

1 reference

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Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control

8 July 2018

1 reference

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Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

8 July 2018

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Human immunodeficiency virus-related microbial translocation and progression of hepatitis C.

8 July 2018

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The biological functions of T helper 17 cell effector cytokines in inflammation

8 July 2018

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Mucosal immune dysfunction in AIDS pathogenesis.

8 July 2018

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Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut.

8 July 2018

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HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

8 July 2018

1 reference

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Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy

8 July 2018

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Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys

8 July 2018

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

8 July 2018

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8 July 2018

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

8 July 2018

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Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors

8 July 2018

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

8 July 2018

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Early antiretroviral therapy for simian immunodeficiency virus infection leads to mucosal CD4+ T-cell restoration and enhanced gene expression regulating mucosal repair and regeneration

8 July 2018

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

8 July 2018

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Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

8 July 2018

1 reference

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CD14 is an acute-phase protein

8 July 2018

1 reference

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Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

8 July 2018

1 reference

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Enteric bacteria, lipopolysaccharides and related cytokines in inflammatory bowel disease: biological and clinical significance

8 July 2018

1 reference

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Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection.

8 July 2018

1 reference

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8 July 2018

1 reference

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Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin Diarrhea/Wasting Syndrome Study Group

8 July 2018

1 reference

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Long-term nonprogressive disease among untreated HIV-infected individuals: clinical implications of understanding immune control of HIV.

8 July 2018

1 reference

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HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells.

27 September 2018

1 reference

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Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126290

Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

27 September 2018

1 reference

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Loss of mucosal CD4 lymphocytes is an early feature of HIV infection.

27 September 2018

1 reference

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CD4+CD25bright T cells in human intestinal lamina propria as regulatory cells

27 September 2018

1 reference

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Elevated plasma lipopolysaccharide is not sufficient to drive natural killer cell activation in HIV-1-infected individuals

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126290

CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients

16 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21471231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21471231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21471231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.02643-10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

21471231

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21471231%20AND%20SRC:MED&resulttype=core&format=json