Nuclear transport as a target for cell growth (Q35058962)

6 August 2017

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title

Nuclear transport as a target for cell growth (English)

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6 August 2017

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Pamela A Silver

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6 August 2017

Tweeny R Kau

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6 August 2017

publication date

1 January 2003

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6 August 2017

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

78-85

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Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Nucleocytoplasmic transport: the last 200 nanometers

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Protein export from the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Transport between the cell nucleus and the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

A new antitumor antibiotic, kazusamycin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Novel antitumor antibiotics, CI-940 (PD 114,720) and PD 114,721. Taxonomy, fermentation and biological activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Effects of leptomycin B on the cell cycle of fibroblasts and fission yeast cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Evidence for a role of CRM1 in signal-mediated nuclear protein export

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Exportin 1 (Crm1p) is an essential nuclear export factor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Phase I trial of elactocin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Accumulating active p53 in the nucleus by inhibition of nuclear export: a novel strategy to promote the p53 tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Nuclear transport and transcription

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

An allosteric drug, o,o'-bismyristoyl thiamine disulfide, suppresses HIV-1 replication through prevention of nuclear translocation of both HIV-1 Tat and NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Inhibition of tumor necrosis factor-alpha -induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Synthesis of NF-kappaB activation inhibitors derived from epoxyquinomicin C

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Regulation and function of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

The MDM2 RING-finger domain is required to promote p53 nuclear export

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Activation of p53 in cervical carcinoma cells by small molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Phosphoinositide kinases

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

An artificial cell-cycle inhibitor isolated from a combinatorial library

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

Targeted modification and transportation of cellular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902562-X

7 January 2021

10.1016/S1359-6446(02)02562-X

Identifiers

DOI

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6 August 2017

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