Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals (Q35007086)

5 August 2017

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title

Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals (English)

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5 August 2017

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Michel Cayouette

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5 August 2017

Martin Raff

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5 August 2017

language of work or name

English

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publication date

1 December 2002

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

1265-1269

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Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question

5 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Asymmetric cell division during animal development

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Control of cell divisions in the nervous system: symmetry and asymmetry

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Inscuteable and numb mediate asymmetric muscle progenitor cell divisions during Drosophila myogenesis

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Asymmetric segregation of Numb and Prospero during cell division

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Numb antagonizes Notch signaling to specify sibling neuron cell fates

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Protein localization during asymmetric cell division

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Asymmetric segregation of Numb in retinal development and the influence of the pigmented epithelium.

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Asymmetric division and polarity of neuroepithelial cells.

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Mouse numb is an essential gene involved in cortical neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Progenitor cell maintenance requires numb and numblike during mouse neurogenesis

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Multiple roles of mouse Numb in tuning developmental cell fates.

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Numb is an endocytic protein

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

The Lnx family proteins function as molecular scaffolds for Numb family proteins

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Identification of a human LNX protein containing multiple PDZ domains

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https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Siah-1 binds and regulates the function of Numb

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Variations on the Notch pathway in neural development

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Identification of a neural stem cell in the adult mammalian central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division.

1 reference

https://api.crossref.org/works/10.1038%2FNN1202-1265

7 January 2021

Identifiers

DOI

10.1038/NN1202-1265

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Dimensions Publication ID

5 August 2017

1052512186

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1 reference