Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? (Q34988256)

5 August 2017

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title

Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? (English)

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5 August 2017

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Shahin Rafii

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5 August 2017

David Lyden

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5 August 2017

Robert Benezra

series ordinal

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5 August 2017

Koichi Hattori

series ordinal

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5 August 2017

Beate Heissig

series ordinal

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5 August 2017

language of work or name

English

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publication date

1 November 2002

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5 August 2017

published in

Nature Reviews Cancer

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

826-835

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

5 August 2017

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Stromal cells can contribute oncogenic signals

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Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

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Origin of endothelial progenitors in human postnatal bone marrow

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Putting the neo into neoangiogenesis

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Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization

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Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors

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Vascular endothelial growth factor is a secreted angiogenic mitogen

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

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Vascular endothelial growth factor (VEGF) and its receptors

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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Regulation of vascular endothelial growth factor receptor-2 (Flk-1) expression in vascular endothelial cells.

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

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Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

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Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

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Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

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Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.

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Vasculogenic mimicry and tumor angiogenesis

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Expression and functional significance of VE-cadherin in aggressive human melanoma cells: role in vasculogenic mimicry

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Can mosaic tumor vessels facilitate molecular diagnosis of cancer?

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Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

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Characterization of hematopoietic cells arising on the textured surface of left ventricular assist devices

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Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells

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Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

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MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

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A role for hematopoietic stem cells in promoting angiogenesis

31 March 2020

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Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma

31 March 2020

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Stem cells, cancer, and cancer stem cells

31 March 2020

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Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

31 March 2020

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The evolving concept of a stem cell: entity or function?

31 March 2020

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Hematopoietic stem cell quiescence maintained by p21cip1/waf1

31 March 2020

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Matrix metalloproteinases: effectors of development and normal physiology

31 March 2020

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

31 March 2020

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Matrix metalloproteinase 9 and vascular endothelial growth factor are essential for osteoclast recruitment into developing long bones

31 March 2020

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Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand

31 March 2020

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Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.

31 March 2020

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KDR receptor: a key marker defining hematopoietic stem cells

31 March 2020

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Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans

31 March 2020

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The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

31 March 2020

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Developmental control of blood cell migration by the Drosophila VEGF pathway

31 March 2020

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VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

31 March 2020

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VEGF receptor 1 stimulates stem-cell recruitment and new hope for angiogenesis therapies

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Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias

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Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration

31 March 2020

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Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model

31 March 2020

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Endothelial cells derived from human embryonic stem cells

31 March 2020

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Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors

31 March 2020

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Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC925

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Dimensions Publication ID

5 August 2017

1015283659

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