Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function. (Q34978484)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18246078%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function (English)

1 reference

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Treacher Collins syndrome

2 January 2020

main subject

1 reference

1 reference

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2 January 2020

Natalie C Jones

1 reference

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2 January 2020

Megan L Lynn

1 reference

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2 January 2020

Karin Gaudenz

1 reference

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2 January 2020

Daisuke Sakai

1 reference

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2 January 2020

Kazushi Aoto

1 reference

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2 January 2020

Jean-Phillipe Rey

1 reference

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2 January 2020

Earl F Glynn

1 reference

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2 January 2020

Lacey Ellington

1 reference

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2 January 2020

Chunying Du

1 reference

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2 January 2020

Jill Dixon

1 reference

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2 January 2020

Michael J Dixon

1 reference

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2 January 2020

language of work or name

English

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publication date

3 February 2008

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2 January 2020

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2 January 2020

volume

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2 January 2020

issue

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2 January 2020

page(s)

125-133

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describes a project that uses

2 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3093709/fullTextXML

inferred from PubMed Central ID database lookup

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Tcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalities

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The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor

8 July 2018

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TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity.

8 July 2018

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Proteomic analysis of human Nop56p-associated pre-ribosomal ribonucleoprotein complexes. Possible link between Nop56p and the nucleolar protein treacle responsible for Treacher Collins syndrome

8 July 2018

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Does the ribosome translate cancer?

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Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways

8 July 2018

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The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice

8 July 2018

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"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

8 July 2018

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The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity

8 July 2018

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Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis

8 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

8 July 2018

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Repression of RNA polymerase I transcription by the tumor suppressor p53

8 July 2018

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

8 July 2018

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TCOF1 gene encodes a putative nucleolar phosphoprotein that exhibits mutations in Treacher Collins Syndrome throughout its coding region

8 July 2018

1 reference

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The mutational spectrum in Treacher Collins syndrome reveals a predominance of mutations that create a premature-termination codon

8 July 2018

1 reference

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p53, the cellular gatekeeper for growth and division

8 July 2018

1 reference

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Treacher Collins syndrome may result from insertions, deletions or splicing mutations, which introduce a termination codon into the gene

8 July 2018

1 reference

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Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression

8 July 2018

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Positional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome. The Treacher Collins Syndrome Collaborative Group

8 July 2018

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The ear deformities in mandibulofacial dysostosis (Treacher Collins syndrome).

8 July 2018

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Nopp 140 shuttles on tracks between nucleolus and cytoplasm

8 July 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

8 July 2018

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8 July 2018

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Reduced hepatic tumor incidence in cyclin G1-deficient mice

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Cyclin G1 associates with MDM2 and regulates accumulation and degradation of p53 protein.

26 October 2018

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Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome.

26 October 2018

1 reference

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26 October 2018

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Mandibulo-facial dysostosis. (Treacher-Collins syndrome)

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18246078

12 December 2020

inferred from PubMed ID database lookup

MANDIBULOFACIAL DYSOSTOSIS, A FAMILIAL STUDY OF FIVE GENERATIONS

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18246078

12 December 2020

inferred from PubMed ID database lookup

Multiple response elements and differential p53 binding control Perp expression during apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18246078

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NM1725

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18246078%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18246078%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

18246078

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18246078%20AND%20SRC:MED&resulttype=core&format=json