Stabilization signals: a novel regulatory mechanism in the ubiquitin/proteasome system (Q34922023)

5 August 2017

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title

Stabilization signals: a novel regulatory mechanism in the ubiquitin/proteasome system (English)

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ubiquitin-proteasome system

5 August 2017

main subject

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Maria G Masucci

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Nico P Dantuma

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5 August 2017

language of work or name

English

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publication date

1 October 2002

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5 August 2017

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5 August 2017

volume

529

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5 August 2017

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5 August 2017

page(s)

22-26

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Mechanisms underlying ubiquitination

5 August 2017

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SCF and Cullin/Ring H2-based ubiquitin ligases

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From UBA to UBX: new words in the ubiquitin vocabulary.

7 January 2021

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The proteasome: paradigm of a self-compartmentalizing protease

7 January 2021

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Substrate targeting in the ubiquitin system

7 January 2021

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The N-end rule: functions, mysteries, uses

7 January 2021

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

7 January 2021

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Degradation of cell proteins and the generation of MHC class I-presented peptides

7 January 2021

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Viral strategies of immune evasion

7 January 2021

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Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

7 January 2021

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Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1.

7 January 2021

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A minimal glycine-alanine repeat prevents the interaction of ubiquitinated I kappaB alpha with the proteasome: a new mechanism for selective inhibition of proteolysis

7 January 2021

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Inhibition of proteasomal degradation by the gly-Ala repeat of Epstein-Barr virus is influenced by the length of the repeat and the strength of the degradation signal

7 January 2021

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Functional p53 chimeras containing the Epstein-Barr virus Gly-Ala repeat are protected from Mdm2- and HPV-E6-induced proteolysis

7 January 2021

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Mechanisms of ubiquitin-mediated, limited processing of the NF-kappaB1 precursor protein p105.

7 January 2021

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Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

7 January 2021

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Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.

7 January 2021

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Taking a bite: proteasomal protein processing

7 January 2021

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ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal

7 January 2021

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Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome

7 January 2021

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Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

7 January 2021

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Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

7 January 2021

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Impairment of the ubiquitin-proteasome system by protein aggregation

7 January 2021

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Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

7 January 2021

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Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

7 January 2021

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Deubiquitinating enzymes: their diversity and emerging roles

7 January 2021

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Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

7 January 2021

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The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme

7 January 2021

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The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin

7 January 2021

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Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

7 January 2021

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UBPY: a growth-regulated human ubiquitin isopeptidase.

7 January 2021

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c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells.

7 January 2021

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Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex

7 January 2021

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Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment

7 January 2021

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Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

7 January 2021

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A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

7 January 2021

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Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair.

7 January 2021

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

7 January 2021

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The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision Repair

7 January 2021

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7 January 2021

Conformational disease

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Inhibition of antigen presentation by the glycine/alanine repeat domain is not conserved in simian homologues of Epstein-Barr virus nuclear antigen 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903252-0

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-5793(02)03252-0

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5 August 2017

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