Good fungi gone bad: the corruption of calcineurin (Q34906798)

5 August 2017

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title

Good fungi gone bad: the corruption of calcineurin (English)

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5 August 2017

Joseph Heitman

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5 August 2017

Deborah S Fox

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5 August 2017

language of work or name

English

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publication date

1 October 2002

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

894-903

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Calcineurin. Structure, function, and inhibition

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcium, calcineurin, and the control of transcription

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin: form and function

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Serine/threonine protein kinases and phosphatases in filamentious fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin: a calcium- and calmodulin-binding protein of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Synergism between the calmodulin-binding and autoinhibitory domains on calcineurin is essential for the induction of their phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

There is communication between all four Ca(2+)-bindings sites of calcineurin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Proton, carbon-13, nitrogen-15 nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Mutations That Perturb Cyclophilin A Ligand Binding Pocket Confer Cyclosporin A Resistance in Saccharomycescerevisiae

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Signal transduction cascades regulating fungal development and virulence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

The Saccharomyces cerevisiae genes (CMP1 and CMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

An essential role of the yeast pheromone-induced Ca2+ signal is to activate calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Ca2+-calmodulin promotes survival of pheromone-induced growth arrest by activation of calcineurin and Ca2+-calmodulin-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Transcription factors of the NFAT family: regulation and function

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylation

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin-dependent nuclear import of the transcription factor Crz1p requires Nmd5p

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Mutational and hyperexpression-induced disruption of bipolar budding in yeast

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Polarized growth controls cell shape and bipolar bud site selection in Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Activated calcineurin confers high tolerance to ion stress and alters the budding pattern and cell morphology of yeast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Regulation of calcineurin gene expression in Schizosaccharomyces pombe. Dependence on the ste11 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

The pathobiology of Paracoccidioides brasiliensis

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Nonfilamentous C. albicans mutants are avirulent

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin is essential for survival during membrane stress in Candida albicans

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin is required for virulence of Cryptococcus neoformans

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin is required for hyphal elongation during mating and haploid fruiting in Cryptococcus neoformans

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcium binding is required for calmodulin function in Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Isolation of the yeast calmodulin gene: calmodulin is an essential protein

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Ca(2+)/calmodulin-dependent kinase is essential for both growth and nuclear division in Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

MID1, a novel Saccharomyces cerevisiae gene encoding a plasma membrane protein, is required for Ca2+ influx and mating

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

A homolog of mammalian, voltage-gated calcium channels mediates yeast pheromone-stimulated Ca2+ uptake and exacerbates the cdc1(Ts) growth defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin subunit B is required for normal vegetative growth in Neurospora crassa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Structure and function analysis of the calcium-related gene spray in Neurospora crassa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

The frost gene of Neurospora crassa is a homolog of yeast cdc1 and affects hyphal branching via manganese homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Cytoskeletal and Ca2+ regulation of hyphal tip growth and initiation

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin is associated with the cytoskeleton of cultured neurons and has a role in the acquisition of polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Impairment of calcineurin function in Neurospora crassa reveals its essential role in hyphal growth, morphology and maintenance of the apical Ca 2+ gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10157

21 January 2018

Identifiers

DOI

10.1002/BIES.10157

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5 August 2017

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