Leptin and reproduction: a review (Q34548469)

2 August 2017

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title

Leptin and reproduction: a review (English)

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2 August 2017

Stergios Moschos

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2 August 2017

Jean L Chan

series ordinal

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2 August 2017

Christos S Mantzoros

series ordinal

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2 August 2017

language of work or name

English

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publication date

1 March 2002

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2 August 2017

published in

Fertility and Sterility

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

433-444

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Positional cloning of the mouse obese gene and its human homologue

2 August 2017

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Expression of leptin receptor in human endometrium and fluctuation during the menstrual cycle

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Insulin and cortisol promote leptin production in cultured human fat cells

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Glucocorticoids as counterregulatory hormones of leptin: toward an understanding of leptin resistance

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Identification and expression analysis of leptin-regulated immediate early response and late target genes

7 January 2021

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Divergent signaling capacities of the long and short isoforms of the leptin receptor

7 January 2021

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Leptin's actions on the reproductive axis: perspectives and mechanisms

7 January 2021

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Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

7 January 2021

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Leptin effects on pulsatile gonadotropin releasing hormone secretion from the adult rat hypothalamus and interaction with cocaine and amphetamine regulated transcript peptide and neuropeptide Y.

7 January 2021

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Cocaine and amphetamine-regulated-transcript peptide mediation of leptin stimulatory effect on the rat gonadotropin-releasing hormone pulse generator in vitro

7 January 2021

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Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat.

7 January 2021

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The effect of leptin on luteinizing hormone release is exerted in the zona incerta and mediated by melanin-concentrating hormone

7 January 2021

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In vitro stimulation of the prepubertal rat gonadotropin-releasing hormone pulse generator by leptin and neuropeptide Y through distinct mechanisms.

7 January 2021

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Targeted disruption of the melanocortin-4 receptor results in obesity in mice

7 January 2021

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Cellular mechanism of pulsatile LHRH release

7 January 2021

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Leptin and leptin receptor expression in normal and neoplastic human pituitary: evidence of a regulatory role for leptin on pituitary cell proliferation

7 January 2021

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Role of leptin in hypothalamic-pituitary function

7 January 2021

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Leptin and leptin receptor expression in rat and mouse pituitary cells

7 January 2021

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Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels

7 January 2021

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The expression of leptin and its receptors in pre-ovulatory human follicles

7 January 2021

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The in vivo and in vitro effects of exogenous leptin on ovulation in the rat.

7 January 2021

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Leptin inhibits gonadotrophin-stimulated granulosa cell progesterone production by antagonizing insulin action

7 January 2021

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Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis.

7 January 2021

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Leptin impairs the synergistic stimulation by transforming growth factor-beta of follicle-stimulating hormone-dependent aromatase activity and messenger ribonucleic acid expression in rat ovarian granulosa cells

7 January 2021

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Leptin directly stimulates aromatase activity in human luteinized granulosa cells

7 January 2021

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Acute stimulation of glucose metabolism in mice by leptin treatment

7 January 2021

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Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation

7 January 2021

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Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

7 January 2021

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Leptin and Leptin Receptor Are Expressed in the Human Endometrium and Endometrial Leptin Secretion Is Regulated by the Human Blastocyst

7 January 2021

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The endometrium as a novel target for leptin: differences in fertility and subfertility

7 January 2021

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Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta

7 January 2021

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Hyperleptinemia of pregnancy associated with the appearance of a circulating form of the leptin receptor.

7 January 2021

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Leptin and neuropeptide Y gene expression in human placenta: ontogeny and evidence for similarities to hypothalamic regulation

7 January 2021

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Modulation of human cytotrophoblastic leptin secretion by interleukin-1alpha and 17beta-oestradiol and its effect on HCG secretion

7 January 2021

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Does leptin exhibit cytokine-like properties in tissues of pregnancy?

7 January 2021

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Leptin receptor in human term placenta: in situ hybridization and immunohistochemical localization

7 January 2021

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Ultradian oscillations of leptin secretion in humans.

7 January 2021

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Human leptin levels are pulsatile and inversely related to pituitary-adrenal function.

7 January 2021

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Twenty-four-hour variation in serum leptin in the elderly.

7 January 2021

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Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women.

7 January 2021

1 reference

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Secretory pattern of leptin and LH during lactational amenorrhoea in breastfeeding normal and polycystic ovarian syndrome women.

7 January 2021

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Episodic leptin release is independent of luteinizing hormone secretion.

7 January 2021

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Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

7 January 2021

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Sex differences in circulating human leptin pulse amplitude: clinical implications

7 January 2021

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Leptin secretion from subcutaneous and visceral adipose tissue in women

7 January 2021

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Differences in circulating concentrations of total, free and bound leptin relate to gender and body composition in adult humans.

7 January 2021

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Serum leptin concentration in cord blood: relationship to birth weight and gender

7 January 2021

1 reference

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Leptin values in placental cord blood of human newborns with normal intrauterine growth after 30-42 weeks of gestation

7 January 2021

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Sex-based differences in serum leptin concentrations from umbilical cord blood at delivery.

7 January 2021

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Leptin levels in pregnant women and newborn infants: gender differences and reduction during the neonatal period

7 January 2021

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Changes in leptin concentration during the early postnatal period: adjustment to extrauterine life?

7 January 2021

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Neonatal cord blood leptin: its relationship to birth weight, body mass index, maternal diabetes, and steroids

7 January 2021

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Postnatal changes of leptin levels in full-term and preterm neonates: their relation to intrauterine growth, gender and testosterone

7 January 2021

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Role of leptin in the neuroendocrine response to fasting

7 January 2021

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Chronic administration of leptin into the lateral ventricle induces sexual maturation in severely food-restricted female rats

7 January 2021

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Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

7 January 2021

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Early onset of reproductive function in normal female mice treated with leptin

7 January 2021

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Leptin accelerates the onset of puberty in normal female mice

7 January 2021

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Accelerated puberty and late-onset hypothalamic hypogonadism in female transgenic skinny mice overexpressing leptin

7 January 2021

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Regulation of gonadal and somatotropic axis by chronic intraventricular infusion of insulin-like growth factor 1 antibody at the initiation of puberty in male rats

7 January 2021

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Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone

7 January 2021

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Serum leptin through childhood and adolescence.

7 January 2021

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Serum leptin levels in normal children: relationship to age, gender, body mass index, pituitary-gonadal hormones, and pubertal stage

7 January 2021

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Effect of puberty on the relationship between circulating leptin and body composition.

7 January 2021

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Leptin Is Inversely Related to Age at Menarche in Human Females

7 January 2021

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A leptin missense mutation associated with hypogonadism and morbid obesity.

7 January 2021

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

7 January 2021

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Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay

7 January 2021

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Alterations in body composition and fat distribution in growth hormone-deficient prepubertal children during growth hormone therapy

7 January 2021

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Effects of anabolic-androgenic steroid use or gonadal testosterone suppression on serum leptin concentration in men.

7 January 2021

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Augmentation of growth hormone secretion during puberty: evidence for a pulse amplitude-modulated phenomenon

7 January 2021

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Increase in free insulin-like growth factor-I levels in precocious and normal puberty

7 January 2021

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Serum leptin concentrations throughout the menstrual cycle

7 January 2021

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Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy

7 January 2021

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Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone

7 January 2021

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Serum leptin concentrations during the menstrual cycle in normal-weight women: effects of an oral triphasic estrogen-progestin medication

7 January 2021

1 reference

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Lack of association between changes in plasma leptin concentration and in food intake during the menstrual cycle.

7 January 2021

1 reference

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Plasma soluble tumor necrosis factor-alpha receptors circulate in proportion to leptin levels during the menstrual cycle in lean but not in obese women

7 January 2021

1 reference

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Changes in plasma leptin during the menstrual cycle

7 January 2021

1 reference

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Correlation between circulating leptin and luteinizing hormone during the menstrual cycle in normal-weight women

7 January 2021

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Leptin levels vary significantly during the menstrual cycle, pregnancy, and in vitro fertilization treatment: possible relation to estradiol

7 January 2021

1 reference

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Leptin concentrations in women in the San Antonio Heart Study: effect of menopausal status and postmenopausal hormone replacement therapy

7 January 2021

1 reference

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Serum leptin concentration in women: effect of age, obesity, and estrogen administration

7 January 2021

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Leptin levels in menopause: effect of estrogen replacement therapy.

7 January 2021

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Plasma leptin levels in obese and non-obese postmenopausal women before and after hormone replacement therapy

7 January 2021

1 reference

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Leptin is not necessary for gestation and parturition but regulates maternal nutrition via a leptin resistance state

7 January 2021

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Elevated leptin concentrations in pregnancy and lactation: possible role as a modulator of substrate utilization

7 January 2021

1 reference

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Longitudinal analysis of maternal serum leptin levels during pregnancy, at birth and up to six weeks after birth: relation to body mass index, skinfolds, sex steroids and umbilical cord blood leptin levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Leptin expression in human mammary epithelial cells and breast milk

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Suppression of leptin during lactation: contribution of the suckling stimulus versus milk production

7 January 2021

1 reference

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Detection and regulation of leptin receptor mRNA in ovine mammary epithelial cells during pregnancy and lactation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

The influence of long-term administration of conjugated estrogens and antiandrogens to serum leptin levels in women with polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Leptin and leptin binding activity in the preovulatory follicle of polycystic ovary syndrome patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with the polycystic ovarian syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Relation between aspects of nutritional disturbance and menstrual activity in primary anorexia nervosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Menstrual and ovulatory disturbance in bulimia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Serum leptin and gonadotropin levels in patients with anorexia nervosa during weight gain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Leptin in relation to resumption of menses in women with anorexia nervosa.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Reduced plasma leptin concentrations in bulimia nervosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Hypoleptinemia in female and male elite gymnasts

7 January 2021

1 reference

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Hypoleptinaemia in patients with anorexia nervosa and in elite gymnasts with anorexia athletica

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Nutritional and endocrine-metabolic aberrations in amenorrheic athletes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Plasma leptin in female athletes: relationship with body fat, reproductive, nutritional, and endocrine factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Nutritional and endocrine-metabolic aberrations in women with functional hypothalamic amenorrhea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Reproductive Hormonal Function in the Genetically Obese (ob/ob) Mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Role of brain insulin receptor in control of body weight and reproduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

IRS-2 pathways integrate female reproduction and energy homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Reduced aminergic synthesis in the hypothalamus of the infertile, genetically diabetic (C57BL/KsJ-db/db) male mouse

7 January 2021

1 reference

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

7 January 2021

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Human leptin receptor gene in obese Japanese subjects: evidence against either obesity-causing mutations or association of sequence variants with obesity

7 January 2021

1 reference

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Growth pattern and age at menarche of obese girls in a transitional society

7 January 2021

1 reference

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Height and weight at menarche and a hypothesis of menarche

7 January 2021

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7 January 2021

Obesity and reproduction

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Putting body weight and osteoporosis into perspective

7 January 2021

1 reference

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Relation of early menarche to high bone mineral density

7 January 2021

1 reference

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Leptin is a potent stimulator of bone growth in ob/ob mice

7 January 2021

1 reference

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Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

7 January 2021

1 reference

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Does leptin have an effect on bone in adult women?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Plasma leptin concentrations in postmenopausal women with osteoporosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Plasma leptin values in relation to bone mass and density and to dynamic biochemical markers of bone resorption and formation in postmenopausal women

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

Influence of insulin-like growth factor-1 and leptin on bone mass in healthy postmenopausal women

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2801%2903010-2

10.1016/S0015-0282(01)03010-2

7 January 2021

Identifiers

DOI

1 reference

2 August 2017

1 reference