Total chemical synthesis of a ribozyme derived from a group I intron (Q34469931)

2 August 2017

title

Total chemical synthesis of a ribozyme derived from a group I intron (English)

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2 August 2017

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S K Whoriskey

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2 August 2017

N Usman

series ordinal

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2 August 2017

J W Szostak

series ordinal

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2 August 2017

language of work or name

English

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publication date

1 March 1995

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Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

2465-2469

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Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

2 August 2017

cites work

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Total chemical synthesis of a 77-nucleotide-long RNA sequence having methionine-acceptance activity

6 July 2018

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Group II intron domain 5 facilitates a trans-splicing reaction

6 July 2018

1 reference

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Design of RNA enzymes distinguishing a single base mutation in RNA.

6 July 2018

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Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis

6 July 2018

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Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena

6 July 2018

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Chemical synthesis of biologically active oligoribonucleotides using beta-cyanoethyl protected ribonucleoside phosphoramidites

6 July 2018

1 reference

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Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns

6 July 2018

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Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity

6 July 2018

1 reference

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Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding

6 July 2018

1 reference

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Reconstitution of enzymatic activity from fragments of M1 RNA

6 July 2018

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Function of specific 2'-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2' modifications

6 July 2018

1 reference

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Synthesis of RNA containing inosine: analysis of the sequence requirements for the 5′ splice site of theTetrahymenagroup I intron

6 July 2018

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The role of a conserved guanosine residue in the hammerhead-type RNA enzyme

6 July 2018

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Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites

6 July 2018

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Selection of a ribozyme that functions as a superior template in a self-copying reaction

6 July 2018

1 reference

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Chemical synthesis of RNA using fast oligonucleotide deprotection chemistry

6 July 2018

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Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function

6 July 2018

1 reference

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A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis

27 October 2018

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12 December 2020

Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes

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12 December 2020

Study of a hammerhead ribozyme containing 2'-modified adenosine residues

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12 December 2020

Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain

1 reference

12 December 2020

Importance of specific adenosine N7-nitrogens for efficient cleavage by a hammerhead ribozyme. A model for magnesium binding

1 reference

12 December 2020

Important 2'-hydroxyl groups within the core of a group I intron

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.92.7.2465

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2 August 2017

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2 August 2017

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