MAP kinase modules: the excursion model and the steps that count (Q34467087)

2 August 2017

1 reference

title

MAP kinase modules: the excursion model and the steps that count (English)

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2 August 2017

author

Elizabeth J. Goldsmith

series ordinal

object named as

Elizabeth J Goldsmith

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2 August 2017

Alexander T Piala

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2 August 2017

John M Humphreys

series ordinal

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2 August 2017

language of work or name

English

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publication date

1 November 2014

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2 August 2017

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inferred from page(s)

published in

Biophysical Journal

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2 August 2017

volume

107

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2 August 2017

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2 August 2017

page(s)

2006-2015

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ERK as a model for systems biology of enzyme kinetics in cells

2 August 2017

cites work

1 reference

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Precisely ordered phosphorylation reactions in the p38 mitogen-activated protein (MAP) kinase cascade

6 July 2018

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Robustness of signal transduction pathways

6 July 2018

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A distinct interaction mode revealed by the crystal structure of the kinase p38α with the MAPK binding domain of the phosphatase MKP5

6 July 2018

1 reference

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Three-dimensional docking in the MAPK p38α.

6 July 2018

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Processive phosphorylation of ERK MAP kinase in mammalian cells

6 July 2018

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Ultrasensitivity in the Regulation of Cdc25C by Cdk1

6 July 2018

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Tunable signal processing in synthetic MAP kinase cascades

6 July 2018

1 reference

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The third conformation of p38α MAP kinase observed in phosphorylated p38α and in solution

6 July 2018

1 reference

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The MAP Kinase Signaling Cascades: A System of Hundreds of Components Regulates a Diverse Array of Physiological Functions

6 July 2018

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Crystal structures of MKK4 kinase domain reveal that substrate peptide binds to an allosteric site and induces an auto-inhibition state

6 July 2018

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Multisite protein phosphorylation--from molecular mechanisms to kinetic models

6 July 2018

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Selectivity of docking sites in MAPK kinases

6 July 2018

1 reference

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MAPK signaling in equations and embryos

6 July 2018

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The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer

6 July 2018

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The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

6 July 2018

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Enzymatic activity and substrate specificity of mitogen-activated protein kinase p38alpha in different phosphorylation states

6 July 2018

1 reference

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Differential regulation and properties of MAPKs

6 July 2018

1 reference

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Substrate competition as a source of ultrasensitivity in the inactivation of Wee1.

6 July 2018

1 reference

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Mechanisms of MAPK signalling specificity

6 July 2018

1 reference

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Multisite protein phosphorylation makes a good threshold but can be a poor switch

6 July 2018

1 reference

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Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs

6 July 2018

1 reference

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Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells.

6 July 2018

1 reference

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Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways

6 July 2018

1 reference

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Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K

6 July 2018

1 reference

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Signaling in small subcellular volumes. II. Stochastic and diffusion effects on synaptic network properties

6 July 2018

1 reference

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Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Structure and regulation of MAPK phosphatases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

6 July 2018

1 reference

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Molecular recognitions in the MAP kinase cascades

6 July 2018

1 reference

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Phosphorylation of Tyr-176 of the yeast MAPK Hog1/p38 is not vital for Hog1 biological activity

6 July 2018

1 reference

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The JNK cascade as a biochemical switch in mammalian cells: ultrasensitive and all-or-none responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

6 July 2018

1 reference

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Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Isolation of hyperactive mutants of the MAPK p38/Hog1 that are independent of MAPK kinase activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Docking domains and substrate-specificity determination for MAP kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Distinct, constitutively active MAPK phosphatases function in Xenopus oocytes: implications for p42 MAPK regulation In vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Mechanistic Studies of the Dual Phosphorylation of Mitogen-activated Protein Kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

The activating dual phosphorylation of MAPK by MEK is nonprocessive

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Ultrasensitivity in the mitogen-activated protein kinase cascade

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Transformation of mammalian cells by constitutively active MAP kinase kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Determination of v-Mos-catalyzed phosphorylation sites and autophosphorylation sites on MAP kinase kinase by ESI/MS.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

An amplified sensitivity arising from covalent modification in biological systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Phorbol ester, serum, and rous sarcoma virus transforming gene product induce similar phosphorylations of ribosomal protein S6

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Insulin secretion: multifactorial regulation for a single process of release. The Minkowski award lecture delivered on September 7, 1972 before the European Association for the study of Diabetes at Madrid, Spain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Activation of glucose uptake by insulin and insulin-like growth factor I in Xenopus oocytes

6 July 2018

1 reference

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An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

6 July 2018

1 reference

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Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Ordered phosphorylation of p42mapk by MAP kinase kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Human T-cell mitogen-activated protein kinase kinases are related to yeast signal transduction kinases

6 July 2018

1 reference

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DynaFit--a software package for enzymology.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Competing docking interactions can bring about bistability in the MAPK cascade

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein-protein interactions.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4223223

The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3.

27 October 2018

1 reference

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Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

27 October 2018

1 reference

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Docking interactions induce exposure of activation loop in the MAP kinase ERK2

9 December 2018

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12 December 2020

Intrinsically active variants of all human p38 isoforms

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12 December 2020

Model analysis of difference between EGF pathway and FGF pathway

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12 December 2020

Induction of maturation of rat follicle‐enclosed oocyte by forskolin

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Regulation and properties of extracellular signal-regulated protein kinases 1, 2, and 3

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Prediction and validation of the distinct dynamics of transient and sustained ERK activation

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10.1016/J.BPJ.2014.09.024

Identifiers

DOI

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2 August 2017

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2 August 2017

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