Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: insights for cGMP-dependent protein kinase agonist design. (Q34463938)

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English	Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: insights for cGMP-dependent protein kinase agonist design.	scientific article

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20 February 2020

Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: insights for cGMP-dependent protein kinase agonist design (English)

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20 February 2020

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Matthew P Blakeley

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20 February 2020

Andrey Kovalevsky

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20 February 2020

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Gilbert Y Huang

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20 February 2020

Oksana O Gerlits

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20 February 2020

Banumathi Sankaran

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20 February 2020

Choel Kim

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20 February 2020

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22 October 2014

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20 February 2020

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20 February 2020

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20 February 2020

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20 February 2020

6725-6727

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20 February 2020

Determinants of ligand selectivity in a cyclic nucleotide–regulated potassium channel

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6 July 2018

Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I

1 reference

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6 July 2018

Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections

1 reference

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6 July 2018

Accessing protein conformational ensembles using room-temperature X-ray crystallography

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6 July 2018

Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222537

6 July 2018

The amino terminus of cGMP-dependent protein kinase Iβ increases the dynamics of the protein's cGMP-binding pockets

1 reference

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6 July 2018

Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222537

6 July 2018

cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4222537

6 July 2018

PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation

1 reference

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6 July 2018

Structure and Rearrangements in the Carboxy-Terminal Region of SpIH Channels

1 reference

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6 July 2018

cGMP-dependent protein kinases in drug discovery

1 reference

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6 July 2018

Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA

1 reference

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6 July 2018

Mutations in the protein kinase A R1alpha regulatory subunit cause familial cardiac myxomas and Carney complex.

1 reference

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6 July 2018

Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

1 reference

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6 July 2018

Fast and slow cyclic nucleotide-dissociation sites in cAMP-dependent protein kinase are transposed in type Ibeta cGMP-dependent protein kinase.

1 reference

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6 July 2018

Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains

1 reference

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6 July 2018

Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3',5'-monophosphorothioates

1 reference

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6 July 2018

Cyclic nucleotide research -- still expanding after half a century

1 reference

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27 October 2018

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10.1021/BI501012V

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20 February 2020

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20 February 2020

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