KCNQ potassium channels: physiology, pathophysiology, and pharmacology (Q34305841)

1 August 2017

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title

KCNQ potassium channels: physiology, pathophysiology, and pharmacology (English)

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1 August 2017

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Robbins J

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1 August 2017

publication date

1 April 2001

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Pharmacology & Therapeutics

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

1-19

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MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Stilbenes and fenamates rescue the loss of I(KS) channel function induced by an LQT5 mutation and other IsK mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Channelopathies of inwardly rectifying potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Molecular diagnosis of the inherited long-QT syndrome in a woman who died after near-drowning

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

M-currents and other potassium currents in bullfrog sympathetic neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Calcium-activated potassium channels expressed from cloned complementary DNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A molecular target for viral killer toxin: TOK1 potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Reduction of spike frequency adaptation and blockade of M‐current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Images in clinical medicine. Congenital long-QT syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The voltage sensor in voltage-dependent ion channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A potassium channel mutation in neonatal human epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The role of ryanodine receptors in the cyclic ADP ribose modulation of the M-like current in rodent m1 muscarinic receptor-transformed NG108-15 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

On the transduction mechanism for muscarine-induced inhibition of M-current in cultured rat sympathetic neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Coupling of muscarinic receptor subtypes to ion channels: experiments on neuroblastoma hybrid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The role of the IsK protein in the specific pharmacological properties of the IKs channel complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Major potassium conductance in type I hair cells from rat semicircular canals: characterization and modulation by nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Homozygous deletion in KVLQT1 associated with Jervell and Lange-Nielsen syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

M-Currents in voltage-clamped mammalian sympathetic neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Ion channel genes and human neurological disease: recent progress, prospects, and challenges.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Inhibition of M-current in cultured rat superior cervical ganglia by linopirdine: mechanism of action studies

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Mutations in the KCNQ4 gene are responsible for autosomal dominant deafness in four DFNA2 families.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A Dominant Negative Isoform of the Long QT Syndrome 1 Gene Product

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Long QT syndrome-associated mutations in the S4-S5 linker of KvLQT1 potassium channels modify gating and interaction with minK subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Molecular aspects of ATP-sensitive K+ channels in the cardiovascular system and K+ channel openers

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Potassium channels still hot.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The aromatic binding site for tetraethylammonium ion on potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K + Channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Both linopirdine- and WAY123,398-sensitive components of I K(M,ng) are modulated by cyclic ADP ribose in NG108-15 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A novel mutation ofKCNQ3 (c.925T?C) in a Japanese family with benign familial neonatal convulsions

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Ionic currents of outer hair cells isolated from the guinea-pig cochlea

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Voltage-gated and inwardly rectifying potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Neuronal KCNQ potassium channels: physiology and role in disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Cloning and functional expression of rKCNQ2 K(+) channel from rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Properties and regulation of the minK potassium channel protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Modulation of spontaneous and stimulation-evoked transmitter release from rat sympathetic neurons by the cognition enhancer linopirdine: insights into its mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (IK(M)) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Voltage-gated ion channels and hereditary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Benign familial neonatal convulsions linked to genetic markers on chromosome 20.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Gain of function mutants: ion channels and G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A new class of inhibitors of cAMP-mediated Cl- secretion in rabbit colon, acting by the reduction of cAMP-activated K+ conductance

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Determination of the subunit stoichiometry of a voltage-activated potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

TRAAK is a mammalian neuronal mechano-gated K+ channel.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Differential expression of outer hair cell potassium currents in the isolated cochlea of the guinea-pig

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Developmental expression of the potassium current IK,n contributes to maturation of mouse outer hair cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

1 reference

7 January 2021

Separation of M-like current and ERG current in NG108-15 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Splicing mutations in KCNQ1: a mutation hot spot at codon 344 that produces in frame transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Genomic organization of the KCNQ1 K+ channel gene and identification of C-terminal mutations in the long-QT syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

DuP 996 (3,3-bis(4-pyrindinylmethyl)-1-phenylindolin-2-one) enhances the stimulus-induced release of acetylcholine from rat brain in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Inhibition of M-type K+ current by linopirdine, a neurotransmitter-release enhancer, in NG108-15 neuronal cells and rat cerebral neurons in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

M-type K+ currents in rat cultured thoracolumbar sympathetic neurones and their role in uracil nucleotide-evoked noradrenaline release

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Potassium channels: some assembly required

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Inhalational anesthetics activate two-pore-domain background K+ channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Structural basis of voltage-gated K+ channel pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Voltage-gated potassium channels: from hyperexcitability to excitement

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A molecular mechanism for electrical tuning of cochlear hair cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Which cardiac potassium channel subtype is the preferable target for suppression of ventricular arrhythmias?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Kinetic and pharmacological properties of the M-current in rodent neuroblastoma x glioma hybrid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

On the mechanism of M-current inhibition by muscarinic m1 receptors in DNA-transfected rodent neuroblastoma x glioma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The real life of voltage-gated K+ channels: more than model behaviour

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Surfing the DNA databases for K+ channels nets yet more diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A constitutively open potassium channel formed by KCNQ1 and KCNE3

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Surface expression and single channel properties of KCNQ2/KCNQ3, M-type K+ channels involved in epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Structure and function of cardiac potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Molecular basis of the long-QT syndrome associated with deafness

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Genomic structure of three long QT syndrome genes: KVLQT1, HERG, and KCNE1.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

A physiological role for ether-à-go-go K+ channels?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The conduction pore of a cardiac potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

TASK-1, a two-pore domain K+ channel, is modulated by multiple neurotransmitters in motoneurons

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

The KCNQ2 potassium channel: splice variants, functional and developmental expression. Brain localization and comparison with KCNQ3

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Mutations in the pore regions of the yeast K+ channel YKC1 affect gating by extracellular K+.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Long QT syndromes and torsade de pointes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Determinant for beta-subunit regulation in high-conductance voltage-activated and Ca(2+)-sensitive K+ channels: an additional transmembrane region at the N terminus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

MinK residues line a potassium channel pore

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Disruption of the epilepsy KCNQ2 gene results in neural hyperexcitability

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Calcium sensitivity of BK-type KCa channels determined by a separable domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Eight potassium channel families revealed by the C. elegans genome project

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Pathophysiological mechanisms of dominant and recessive KVLQT1 K+ channel mutations found in inherited cardiac arrhythmias

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

YKC1 encodes the depolarization‐activated K+ channel in the plasma membrane of yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

Dysfunction of M-channel enhances propagation of neuronal excitability in rat hippocampus monitored by multielectrode dish and microdialysis systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2801%2900116-4

7 January 2021

10.1016/S0163-7258(01)00116-4

Identifiers

DOI

1 reference

1 August 2017

1 reference