Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signa (Q34220264)

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scientific article published on June 1, 1992

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English	Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signa	scientific article published on June 1, 1992

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signa (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signals (English)

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534818

6 October 2022

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S. Pahwa

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6 October 2022

author name string

N. Oyaizu

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534818

6 October 2022

N. Chirmule

2

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6 October 2022

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1 June 1992

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31 July 2017

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https://europepmc.org/articles/PMC295879

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534818

6 October 2022

https://europepmc.org/articles/PMC295879?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534818

6 October 2022

Journal of Clinical Investigation

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31 July 2017

89

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Europe PubMed Central

PubMed publication ID

31 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1807-1816

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Mouse rDNA: sequences and evolutionary analysis of spacer and mature RNA regions

1 reference

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5 July 2018

Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Molecular cloning of human interleukin 2 cDNA and its expression inE. coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Ethnic heterogeneity in the distribution of the OKT4 antigen on lymphocytes: studies in three black families.

1 reference

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5 July 2018

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Differential requirements for the induction of interleukin 2 responsiveness in L3T4+ and Lyt-2+ T cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck)

1 reference

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5 July 2018

Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens

1 reference

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5 July 2018

The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Early signal transduction by the antigen receptor without commitment to T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Mechanisms regulating the level of IL-2 mRNA in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

The role of the L3T4 molecule in mitogen and antigen-activated signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

T-lymphocyte activation: the role of protein kinase C and the bifurcating inositol phospholipid signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

CD4 and CD8 molecules can physically associate with the same T-cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Functionally distinct NF-kappa B binding sites in the immunoglobulin kappa and IL-2 receptor alpha chain genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

The carboxy-terminal sequence of p56lck can regulate p60c-src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Transmembrane ion fluxes during activation of human T lymphocytes: role of Ca2+, Na+/H+ exchange and phospholipid turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Perturbation of the T4 molecule transmits a negative signal to T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Human immunodeficiency virus type 1 envelope glycoprotein gp120 produces immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Stimulation of the phosphatidylinositol pathway can induce T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

1 reference

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Protein kinase C-independent activation of nuclear factor kappa B by tumor necrosis factor

1 reference

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5 July 2018

T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Effect of human immunodeficiency virus gp120 glycoprotein on the association of the protein tyrosine kinase p56lck with CD4 in human T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Regulatory role of CD4/L3T4 molecules in IL-2 production by affecting intracellular Ca2+ concentration of T cell clone stimulated with soluble anti-CD3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

HIV-gp120 can block CD4-class II MHC-mediated adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Inhibition of functional properties of tetanus antigen-specific T-cell clones by envelope glycoprotein GP120 of human immunodeficiency virus.

1 reference

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5 July 2018

CD4, CD8 and the TCR-CD3 complex: a novel class of protein-tyrosine kinase receptor

1 reference

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5 July 2018

T cell antigen receptor activation pathways: The tyrosine kinase connection

1 reference

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5 July 2018

Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.

1 reference

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5 July 2018

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1 reference

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5 July 2018

No T-cell tyrosine protein kinase signalling or calcium mobilization after CD4 association with HIV-1 or HIV-1 gp120

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

5 July 2018

A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate

1 reference

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5 July 2018

The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295879

28 October 2018

Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4.

1 reference

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28 October 2018

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin

1 reference

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28 October 2018

A common pathway for T lymphocyte activation involving both the CD3-Ti complex and CD2 sheep erythrocyte receptor determinants

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 molecules are associated with the antigen receptor complex on activated but not resting T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction through CD4 receptors: stimulatory vs. inhibitory activity is regulated by CD4 proximity to the CD3/T cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accessory cell independent proliferation of human T4 cells stimulated by immobilized monoclonal antibodies to CD3

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular activation signal requirements for the induction of IL-2 responsiveness in resting T cell subsets in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of the human T cell antigen receptor zeta-chain: activation via CD3 but not CD2

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and characterization of interleukin-2-independent antigen-specific human T cell clones that produce multiple lymphokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MHC-binding and gp120-binding functions of CD4 are separable

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the interleukin 2 receptor expression on T cells by multiple B-lymphotropic lymphokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accessory cell function in the Con A response: role of Ia-positive and Ia-negative accessory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

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Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI115785

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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