Neuroblastoma: biological insights into a clinical enigma (Q34180699)

31 July 2017

1 reference

title

Neuroblastoma: biological insights into a clinical enigma (English)

1 reference

31 July 2017

1 reference

Garrett M Brodeur

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 March 2003

1 reference

31 July 2017

published in

Nature Reviews Cancer

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

31 July 2017

page(s)

203-216

1 reference

Familial neuroblastoma. Case reports, literature review, and etiologic considerations

31 July 2017

cites work

1 reference

Molecular biology of neuroblastoma

31 March 2020

1 reference

Monozygotic siblings discordant for neuroblastoma: etiologic implications

31 March 2020

1 reference

Synchronous neuroblastoma and von Recklinghausen's disease: a review of the literature

31 March 2020

1 reference

Localization of a hereditary neuroblastoma predisposition gene to 16p12-p13

31 March 2020

1 reference

High incidence of constitutional balanced translocations in neuroblastoma

31 March 2020

1 reference

Detailed molecular analysis of 1p36 in neuroblastoma

31 March 2020

1 reference

Current urinary mass screening for catecholamine metabolites at 6 months of age may be detecting only a small portion of high-risk neuroblastomas: a chromosome and N-myc amplification study

31 March 2020

1 reference

Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma

31 March 2020

1 reference

Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study

31 March 2020

1 reference

Mechanism and relevance of ploidy in neuroblastoma

31 March 2020

1 reference

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

31 March 2020

1 reference

Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc

31 March 2020

1 reference

MYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells

31 March 2020

1 reference

Isolation and structural analysis of a 1.2-megabase N-myc amplicon from a human neuroblastoma

31 March 2020

1 reference

Molecular biology and genetics of human neuroblastoma

31 March 2020

1 reference

High-resolution mapping of a 130-kb core region of the MYCN amplicon in neuroblastomas

31 March 2020

1 reference

MYCN is the only highly expressed gene from the core amplified domain in human neuroblastomas

31 March 2020

1 reference

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

31 March 2020

1 reference

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

31 March 2020

1 reference

Biology and genetics of human neuroblastomas.

31 March 2020

1 reference

Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma

31 March 2020

1 reference

Human neuroblastoma cell lines that express N-myc without gene amplification.

31 March 2020

1 reference

Autoregulation of the human N-myc oncogene is disrupted in amplified but not single-copy neuroblastoma cell lines.

31 March 2020

1 reference

Prognostic significance of MYCN oncogene expression in childhood neuroblastoma

31 March 2020

1 reference

MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN

31 March 2020

1 reference

Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification

31 March 2020

1 reference

Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma

31 March 2020

1 reference

Loss of Heterozygosity at 1p36 Independently Predicts for Disease Progression But Not Decreased Overall Survival Probability in Neuroblastoma Patients: A Children’s Cancer Group Study

31 March 2020

1 reference

Coamplification of the L-myc and N-myc oncogenes in a neuroblastoma cell line

31 March 2020

1 reference

Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP

31 March 2020

1 reference

Comparative genomic hybridization (CGH) analysis of neuroblastomas--an important methodological approach in paediatric tumour pathology

31 March 2020

1 reference

Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.

31 March 2020

1 reference

Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma

31 March 2020

1 reference

Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma

31 March 2020

1 reference

Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes.

31 March 2020

1 reference

Breakpoint position on 17q identifies the most aggressive neuroblastoma tumors

31 March 2020

1 reference

High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma

31 March 2020

1 reference

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3

31 March 2020

1 reference

Fine mapping of a tumour suppressor candidate gene region in 1p36.2-3, commonly deleted in neuroblastomas and germ cell tumours

31 March 2020

1 reference

Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted

31 March 2020

1 reference

Smallest region of overlapping deletion in 1p36 in human neuroblastoma: a 1 Mbp cosmid and PAC contig

31 March 2020

1 reference

Identification of a 1-megabase consensus region of deletion at 1p36.3 in primary neuroblastomas

31 March 2020

1 reference

Comprehensive analysis of chromosome 1p deletions in neuroblastoma

31 March 2020

1 reference

Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line

31 March 2020

1 reference

Homozygous deletion in a neuroblastoma cell line defined by a high-density STS map spanning human chromosome band 1p36.

31 March 2020

1 reference

Deletion of chromosome 11 and of 14q sequences in neuroblastoma

31 March 2020

1 reference

Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lackingMYCN amplification

31 March 2020

1 reference

Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas

31 March 2020

1 reference

Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss

31 March 2020

1 reference

Loss of heterozygosity for chromosome 14q in neuroblastoma

31 March 2020

1 reference

Low frequency of the p53 gene mutations in neuroblastoma

31 March 2020

1 reference

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

31 March 2020

1 reference

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

31 March 2020

1 reference

Structural and functional analysis of cyclin-dependent kinase inhibitor genes (CDKN2A, CDKN2B, and CDKN2C) in neuroblastoma.

31 March 2020

1 reference

Molecular analysis of the cyclin-dependent kinase inhibitor family: p16(CDKN2/MTS1/INK4A), p18(INK4C) and p27(Kip1) genes in neuroblastomas

31 March 2020

1 reference

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras

31 March 2020

1 reference

Neurofibromatosis type 1 gene mutations in neuroblastoma

31 March 2020

1 reference

Neurotrophin receptor structure and interactions

31 March 2020

1 reference

Trk receptors: mediators of neurotrophin action

31 March 2020

1 reference

Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma

31 March 2020

1 reference

Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas

31 March 2020

1 reference

Role of ploidy, chromosome 1p, and Schwann cells in the maturation of neuroblastoma

31 March 2020

1 reference

Neuroblastoma cells provoke Schwann cell proliferation in vitro

31 March 2020

1 reference

Role of neurotrophins and their receptors in human neuroblastomas: a primary culture study

31 March 2020

1 reference

Expression and function of TRK-B and BDNF in human neuroblastomas

31 March 2020

1 reference

A BDNF autocrine loop in adult sensory neurons prevents cell death.

31 March 2020

1 reference

Expression of neurotrophin receptor TrkA inhibits angiogenesis in neuroblastoma

31 March 2020

1 reference

Expression of mRNA for the neurotrophin receptor trkC in neuroblastomas with favourable tumour stage and good prognosis

31 March 2020

1 reference

Neurotrophins in cell survival/death decisions.

31 March 2020

1 reference

The many faces of p75NTR.

31 March 2020

1 reference

Expression of the multidrug resistance, MDR1, gene in neuroblastomas

31 March 2020

1 reference

P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma

31 March 2020

1 reference

Expression of the Gene for Multidrug-Resistance–Associated Protein and Outcome in Patients with Neuroblastoma

31 March 2020

1 reference

Correlating telomerase activity levels with human neuroblastoma outcomes

31 March 2020

1 reference

Do the ends justify the means?

31 March 2020

1 reference

Induction of apoptosis by p75 neurotrophin receptor in human neuroblastoma cells

31 March 2020

1 reference

In situ detection of DNA fragmentation and expression of bcl-2 in human neuroblastoma: relation to apoptosis and spontaneous regression

31 March 2020

1 reference

Genetic parameters of neuroblastomas

31 March 2020

1 reference

Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.

31 March 2020

1 reference

Serum neuron-specific enolase in children with neuroblastoma. Relationship to stage and disease course.

31 March 2020

1 reference

Detection of a tumour-associated ganglioside in plasma of patients with neuroblastoma

31 March 2020

1 reference

Serum lactic dehydrogenase, an indicator of tumor activity in neuroblastoma

31 March 2020

1 reference

Serum lactate dehydrogenase in childhood neuroblastoma. A Pediatric Oncology Group recursive partitioning study

31 March 2020

1 reference

Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas

31 March 2020

1 reference

Clinical relevance of CD44 cell-surface expression and N-myc gene amplification in a multicentric analysis of 121 pediatric neuroblastomas

31 March 2020

1 reference

The International Neuroblastoma Risk Groups (INRG): a preliminary report

31 March 2020

1 reference

Congenital neuroblastoma, neuroblastoma in situ, and the normal fetal development of the adrenal

31 March 2020

1 reference

Neuroblastoma. Mass screening for early detection and its prognosis

31 March 2020

1 reference

History and current status of neuroblastoma screening in Japan

31 March 2020

1 reference

Screening for neuroblastoma

31 March 2020

1 reference

A population-based study of the usefulness of screening for neuroblastoma

31 March 2020

1 reference

Chromosomes and screening for neuroblastoma

31 March 2020

1 reference

Chromosome findings and prognosis in 15 patients with neuroblastoma found by VMA mass screening

31 March 2020

1 reference

Biological aspects of neuroblastomas identified by mass screening in Quebec

31 March 2020

1 reference

Screening of infants and mortality due to neuroblastoma

31 March 2020

1 reference

Neuroblastoma Screening at One Year of Age

31 March 2020

1 reference

Disomy 1 with terminal 1p deletion is frequent in mass-screening-negative/late-presenting neuroblastomas in young children, but not in mass-screening-positive neuroblastomas in infants

31 March 2020

1 reference

Clinical and biologic characteristics for recurring neuroblastoma at mass screening cases in Japan

31 March 2020

1 reference

SAGE analysis of neuroblastoma reveals a high expression of the human homologue of the Drosophila Delta gene

31 March 2020

1 reference

The MEIS1 oncogene is highly expressed in neuroblastoma and amplified in cell line IMR32

31 March 2020

1 reference

Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

31 March 2020

1 reference

Targeted expression of MYCN causes neuroblastoma in transgenic mice

31 March 2020

1 reference

Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in a murine neuroblastoma model.

31 March 2020

1 reference

Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines

31 March 2020

1 reference

Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma.

31 March 2020

1 reference

Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group

31 March 2020

1 reference

Effector mechanisms of fenretinide-induced apoptosis in neuroblastoma.

31 March 2020

1 reference

Differentiating agents in pediatric malignancies: retinoids in neuroblastoma.

31 March 2020

1 reference

Antisense oligonucleotides as therapeutic agents

31 March 2020

1 reference

Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma

31 March 2020

1 reference

The angiogenesis inhibitor TNP-470 reduces the growth rate of human neuroblastoma in nude rats

31 March 2020

1 reference

Inhibition of tumor growth in a human neuroblastoma xenograft model with TNP-470.

31 March 2020

1 reference

Lack of antitumor activity of recombinant endostatin in a human neuroblastoma xenograft model

31 March 2020

1 reference

Distinct response of experimental neuroblastoma to combination antiangiogenic strategies

31 March 2020

1 reference

Gene therapy-mediated expression by tumor cells of the angiogenesis inhibitor flk-1 results in inhibition of neuroblastoma growth in vivo

31 March 2020

1 reference

Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice

31 March 2020

1 reference

A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group

31 March 2020

1 reference

Phase I trial of a human-mouse chimeric anti-disialoganglioside monoclonal antibody ch14.18 in patients with refractory neuroblastoma and osteosarcoma.

31 March 2020

1 reference

First line targeted radiotherapy, a new concept in the treatment of advanced stage neuroblastoma

31 March 2020

1 reference

Phase I dose escalation of 131I-metaiodobenzylguanidine with autologous bone marrow support in refractory neuroblastoma

31 March 2020

1 reference

Pilot study of iodine-131-metaiodobenzylguanidine in combination with myeloablative chemotherapy and autologous stem-cell support for the treatment of neuroblastoma

31 March 2020

1 reference

Neuroendocrine tumors of the sinonasal tract. Results of a prospective study incorporating chemotherapy, surgery, and combined proton-photon radiotherapy

31 March 2020

1 reference

Neuroblastomas with chromosome 11q loss and single copy MYCN comprise a biologically distinct group of tumours with adverse prognosis

31 March 2020

1 reference

Successful treatment of esthesioneuroblastoma and neuroendocrine carcinoma with combined chemotherapy and proton radiation. Results in 9 cases

31 March 2020

1 reference

Infant cancer in the U.S.: histology-specific incidence and trends, 1973 to 1992.

31 March 2020

1 reference

Biologic factors determine prognosis in infants with stage IV neuroblastoma: A prospective Children's Cancer Group study

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC1014

1 reference

Dimensions Publication ID

31 July 2017

1008818340

0 references

1 reference