The relationship between the roles of BRCA genes in DNA repair and cancer predisposition (Q34163219)

31 July 2017

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title

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition (English)

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31 July 2017

Andrew Tutt

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31 July 2017

Alan Ashworth

series ordinal

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31 July 2017

language of work or name

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1 December 2002

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Trends in Molecular Medicine

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

571-576

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THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

31 July 2017

cites work

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

New complexities for BRCA1 and BRCA2.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Cancer susceptibility and the functions of BRCA1 and BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Defying death after DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Brca1 controls homology-directed DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

DNA double strand break repair in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Nucleotide excision repair in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

BRCA1 required for transcription-coupled repair of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Genomic instability in mice lacking histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Involvement of Brca2 in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Disruption of Brca2 increases the spontaneous mutation rate in vivo: synergism with ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Cancer. BRCA2 enters the fray

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Biallelic inactivation of BRCA2 in Fanconi anemia

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Biomedicine. D-Day for BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Breast cancer and Fanconi anemia: what are the connections?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

The emerging genetic and molecular basis of Fanconi anaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Dominant Negative ATM Mutations in Breast Cancer Families

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902434-6

7 January 2021

10.1016/S1471-4914(02)02434-6

Identifiers

DOI

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31 July 2017

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