Jak2 is involved in c-Myc induction by Bcr-Abl (Q34153616)

31 July 2017

title

Jak2 is involved in c-Myc induction by Bcr-Abl (English)

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31 July 2017

Ralph B Arlinghaus

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31 July 2017

Shanhai Xie

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31 July 2017

Hui Lin

series ordinal

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31 July 2017

Tong Sun

series ordinal

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31 July 2017

language of work or name

English

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publication date

1 October 2002

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

7137-7146

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Differential complementation of Bcr-Abl point mutants with c-Myc

31 July 2017

cites work

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Degradation of nuclear oncoproteins by the ubiquitin system in vitro

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Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation

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Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades

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Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor

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myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome

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Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

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Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells

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Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

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P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

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Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences

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Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

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Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

21 January 2018

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Human proto-oncogene N-myc encodes nuclear proteins that bind DNA

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A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

21 January 2018

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Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2.

21 January 2018

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Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbeta

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Dominant negative MYC blocks transformation by ABL oncogenes

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

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Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

21 January 2018

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

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STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction

21 January 2018

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JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells.

21 January 2018

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Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation

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Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity

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Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

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inferred from DOI database lookup

7 January 2021

based on heuristic

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205942

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Dimensions Publication ID

31 July 2017

1011394029

0 references

1 reference