Hyperthermia inhibits recombination repair of gemcitabine-stalled replication forks. (Q34137713)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25128695%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Hyperthermia inhibits recombination repair of gemcitabine-stalled replication forks (English)

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12 March 2020

Mustafa Raoof

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12 March 2020

Cihui Zhu

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12 March 2020

Brandon T Cisneros

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12 March 2020

Heping Liu

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12 March 2020

Steven A Curley

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12 March 2020

language of work or name

English

0 references

publication date

15 August 2014

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Journal of the National Cancer Institute

12 March 2020

published in

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12 March 2020

volume

106

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12 March 2020

issue

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Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining

12 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Identification of Mre11 as a target for heat radiosensitization

28 July 2018

1 reference

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Hyperthermia alters the interaction of proteins of the Mre11 complex in irradiated cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

More forks on the road to replication stress recovery

28 July 2018

1 reference

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Noninvasive radiofrequency field destruction of pancreatic adenocarcinoma xenografts treated with targeted gold nanoparticles

28 July 2018

1 reference

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Purified human BRCA2 stimulates RAD51-mediated recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

PARP-1 transcriptional activity is regulated by sumoylation upon heat shock

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Exonuclease function of human Mre11 promotes deletional nonhomologous end joining

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Cell-cycle coordination between DNA replication and recombination revealed by a vertebrate N-end rule degron-Rad51.

28 July 2018

1 reference

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Clonogenic assay of cells in vitro.

28 July 2018

1 reference

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Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Pathways for mitotic homologous recombination in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Characterization of homologous recombination induced by replication inhibition in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Overexpression of p53 in a large series of patients with hepatocellular carcinoma: a clinicopathological correlation.

28 July 2018

1 reference

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Expression of P-glycoprotein in hepatocellular carcinoma: a potential marker of prognosis

28 July 2018

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Overexpression of the MDR1 gene and P-glycoprotein in human hepatocellular carcinoma

28 July 2018

1 reference

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Increased PARP-1 levels in nuclear matrix isolated from heat shock treated rat liver.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Fixed-dose-rate gemcitabine infusion in patients with advanced pancreatic or biliary tree adenocarcinoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Sorafenib in advanced hepatocellular carcinoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

Synergistic interaction of hyperthermia and Gemcitabine in lung cancer

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155430

The effects of hyperthermia on DNA replication in HeLa cells

28 October 2018

1 reference

12 December 2020

Action of 2',2'-difluorodeoxycytidine on DNA synthesis

1 reference

12 December 2020

Factors affecting long-term outcome after hepatic resection for hepatocellular carcinoma

1 reference

12 December 2020

Excision of 2',2'-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA

1 reference

12 December 2020

Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1

1 reference

12 December 2020

Translocation of MRE11 from the Nucleus to the Cytoplasm as a Mechanism of Radiosensitization by Heat

1 reference

12 December 2020

Identifiers

DOI

10.1093/JNCI/DJU183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25128695%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25128695%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

25128695

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25128695%20AND%20SRC:MED&resulttype=core&format=json