Depression-resistant endophenotype in mice overexpressing cannabinoid CB(2) receptors (Q34116825)

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8 February 2020

title

Depression-resistant endophenotype in mice overexpressing cannabinoid CB(2) receptors (English)

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8 February 2020

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8 February 2020

Alfonso Gutiérrez-Adán

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8 February 2020

M S García-Gutiérrez

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8 February 2020

J Manzanares

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language of work or name

English

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publication date

1 August 2010

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British Journal of Pharmacology

8 February 2020

published in

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8 February 2020

volume

160

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8 February 2020

issue

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8 February 2020

page(s)

1773-1784

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The future of endocannabinoid-oriented clinical research after CB1 antagonists.

8 February 2020

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Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression

5 July 2018

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Emerging strategies for exploiting cannabinoid receptor agonists as medicines

5 July 2018

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Interferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain

5 July 2018

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Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain

5 July 2018

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Age-dependent effects of chronic stress on brain plasticity and depressive behavior

5 July 2018

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Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment

5 July 2018

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5 July 2018

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Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal

5 July 2018

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Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

5 July 2018

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CB2 receptors in the brain: role in central immune function

5 July 2018

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Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice

5 July 2018

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Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists

5 July 2018

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Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain

5 July 2018

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Chronic mild stress inhibits BDNF protein expression and CREB activation in the dentate gyrus but not in the hippocampus proper

5 July 2018

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COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

5 July 2018

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Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain

5 July 2018

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The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats

5 July 2018

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Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders

5 July 2018

1 reference

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Identification and functional characterization of brainstem cannabinoid CB2 receptors

5 July 2018

1 reference

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Antidepressant-like and anorectic effects of the cannabinoid CB1 receptor inverse agonist AM251 in mice

5 July 2018

1 reference

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Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains

5 July 2018

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Finding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments

5 July 2018

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The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions

5 July 2018

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Preclinical models: status of basic research in depression

5 July 2018

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Assessing antidepressant activity in rodents: recent developments and future needs

5 July 2018

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Neurobiology of depression

5 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

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5 July 2018

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5 July 2018

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Control of the cell survival/death decision by cannabinoids

5 July 2018

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Altered fear circuits in 5-HT(1A) receptor KO mice

5 July 2018

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Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation

5 July 2018

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Hippocampal atrophy in recurrent major depression

5 July 2018

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Molecular characterization of a peripheral receptor for cannabinoids

5 July 2018

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Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

5 July 2018

1 reference

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The effects of chronic antidepressant treatment in an animal model of anxiety

5 July 2018

1 reference

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Up-regulation of opiate receptors following chronic naloxone treatment in aged rats

5 July 2018

1 reference

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An animal model of anhedonia

5 July 2018

1 reference

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Chronic mild stress-induced anhedonia: a realistic animal model of depression

5 July 2018

1 reference

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Depression: a new animal model sensitive to antidepressant treatments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936848

Guide to Receptors and Channels (GRAC), 3rd edition

5 July 2018

1 reference

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Effects of chronic mild stress on performance in behavioural tests relevant to anxiety and depression.

21 January 2018

1 reference

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Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment

21 January 2018

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Chronic mild stress and sucrose consumption: validity as a model of depression.

21 January 2018

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Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents

21 January 2018

1 reference

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AM630 antagonism of cannabinoid-stimulated [35S]GTP gamma S binding in the mouse brain

21 January 2018

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Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims

21 January 2018

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The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels

21 January 2018

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Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms

21 January 2018

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Chronic mild stress impairs cognition in mice: from brain homeostasis to behavior.

21 January 2018

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23 Punch sampling biopsy technique

21 January 2018

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Antagonist-induced micro-opioid receptor up-regulation decreases G-protein receptor kinase-2 and dynamin-2 abundance in mouse spinal cord

21 January 2018

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Altered CB receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine.

21 January 2018

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Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses

21 January 2018

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Activation of endocannabinoid transmission induces antidepressant-like effects in rats.

21 January 2018

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Methods to study the behavioral effects and expression of CB2 cannabinoid receptor and its gene transcripts in the chronic mild stress model of depression

28 October 2018

1 reference

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The cannabinoid CB1receptor and the endocannabinoid anandamide: possible antidepressant targets

28 October 2018

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12 December 2020

3D MRI studies of neuroanatomic changes in unipolar major depression: the role of stress and medical comorbidity

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12 December 2020

AM630, a competitive cannabinoid receptor antagonist

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12 December 2020

Pharmacological validation of the chronic mild stress model of depression

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12 December 2020

Individual differences in response to imipramine in the mouse tail suspension test

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12 December 2020

A therapeutic role for cannabinoid CB1 receptor antagonists in major depressive disorders

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12 December 2020

10.1111/J.1476-5381.2010.00819.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20649579%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20649579%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

20649579

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20649579%20AND%20SRC:MED&resulttype=core&format=json