Deconstructing PML-induced premature senescence (Q34089507)

30 July 2017

title

Deconstructing PML-induced premature senescence (English)

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30 July 2017

Olivier Kirsh

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30 July 2017

Oliver Bischof

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30 July 2017

Mark Pearson

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30 July 2017

Koji Itahana

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30 July 2017

Pier Giuseppe Pelicci

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30 July 2017

Anne Dejean

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30 July 2017

language of work or name

English

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publication date

1 July 2002

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

3358-3369

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The serial cultivation of human diploid cell strains

30 July 2017

cites work

1 reference

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Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

5 July 2018

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Cell senescence and cancer

5 July 2018

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

5 July 2018

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p53 mutant mice that display early ageing-associated phenotypes

5 July 2018

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

5 July 2018

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DNA viruses and viral proteins that interact with PML nuclear bodies

5 July 2018

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PML interaction with p53 and its role in apoptosis and replicative senescence

5 July 2018

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5 July 2018

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Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot

5 July 2018

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PML protein isoforms and the RBCC/TRIM motif

5 July 2018

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Putting the stress on senescence

5 July 2018

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Cellular senescence as a tumor-suppressor mechanism

5 July 2018

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

5 July 2018

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Negative control of p53 by Sir2alpha promotes cell survival under stress

5 July 2018

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High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth

5 July 2018

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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

5 July 2018

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Regulation of cellular senescence by p53.

5 July 2018

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Post-translational modifications and activation of p53 by genotoxic stresses

5 July 2018

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Regulation and localization of the Bloom syndrome protein in response to DNA damage

5 July 2018

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Telomerase and human tumorigenesis

5 July 2018

1 reference

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Telomeres and telomerase: implications for cancer and aging

5 July 2018

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Regulation of p53 activity in nuclear bodies by a specific PML isoform

5 July 2018

1 reference

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Genes involved in senescence and immortalization

5 July 2018

1 reference

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PML is induced by oncogenic ras and promotes premature senescence

5 July 2018

1 reference

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NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Tumor suppressors and oncogenes in cellular senescence.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

The transcriptional role of PML and the nuclear body

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Role of SUMO-1-modified PML in nuclear body formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

The PML nuclear bodies: actors or extras?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

5 July 2018

1 reference

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Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Identification of three major sentrinization sites in PML

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Cooperation between the RING + B1-B2 and coiled-coil domains of PML is necessary for its effects on cell survival.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Role of PML in cell growth and the retinoic acid pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Extension of life-span by introduction of telomerase into normal human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

WAF1, a potential mediator of p53 tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

PML, a growth suppressor disrupted in acute promyelocytic leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126090

Evidence for separate ND10-binding and homo-oligomerization domains of Sp100

28 October 2018

1 reference

12 December 2020

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

12 December 2020

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

12 December 2020

Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body

1 reference

12 December 2020

Fusion proteins between PML and alpha-RAR in acute promyelocytic leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDF341

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30 July 2017

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30 July 2017

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