Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM (Q33952887)

30 July 2017

title

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM (English)

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30 July 2017

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Lynda Chin

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30 July 2017

William C Hahn

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30 July 2017

author name string

W Ruprecht Wiedemeyer

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30 July 2017

Ian F Dunn

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30 July 2017

Steven N Quayle

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30 July 2017

Jianhua Zhang

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30 July 2017

Milan G Chheda

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30 July 2017

Gavin P Dunn

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30 July 2017

Li Zhuang

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30 July 2017

Joseph Rosenbluh

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30 July 2017

Shujuan Chen

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30 July 2017

Yonghong Xiao

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30 July 2017

Geoffrey I Shapiro

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30 July 2017

language of work or name

English

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publication date

7 June 2010

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

107

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30 July 2017

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30 July 2017

page(s)

11501-11506

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Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts

30 July 2017

cites work

1 reference

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PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

5 July 2018

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Expression levels of p18INK4C modify the cellular efficacy of cyclin-dependent kinase inhibitors via regulation of Mcl-1 expression in tumor cell lines

5 July 2018

1 reference

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Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells

5 July 2018

1 reference

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Cell cycle, CDKs and cancer: a changing paradigm

5 July 2018

1 reference

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

Identification of p18 INK4c as a tumor suppressor gene in glioblastoma multiforme

5 July 2018

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Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

5 July 2018

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CDK inhibitors in cancer therapy: what is next?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

Cdk1 is sufficient to drive the mammalian cell cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

5 July 2018

1 reference

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Statistical practice in high-throughput screening data analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

5 July 2018

1 reference

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

5 July 2018

1 reference

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Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts.

5 July 2018

1 reference

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The RB and p53 pathways in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

Epidermal growth factor receptor and Ink4a/Arf

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1001613107

Cyclin-dependent kinase 6 (CDK6) amplification in human gliomas identified using two-dimensional separation of genomic DNA.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895056

CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20534551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1001613107

1 reference

30 July 2017

0 references

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30 July 2017

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