Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members (Q33929533)

30 July 2017

title

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members (English)

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30 July 2017

T Mizutani

1 reference

30 July 2017

Y Taniguchi

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30 July 2017

T Aoki

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30 July 2017

N Hashimoto

1 reference

30 July 2017

T Honjo

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30 July 2017

language of work or name

English

0 references

publication date

17 July 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

9026-9031

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Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate

30 July 2017

cites work

1 reference

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Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

5 July 2018

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A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

5 July 2018

1 reference

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Notch signalling via RBP-J promotes myeloid differentiation.

5 July 2018

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Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

5 July 2018

1 reference

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

5 July 2018

1 reference

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

5 July 2018

1 reference

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Mice lacking both presenilin genes exhibit early embryonic patterning defects

5 July 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

5 July 2018

1 reference

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Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

5 July 2018

1 reference

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Translating cell biology into therapeutic advances in Alzheimer's disease

5 July 2018

1 reference

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Notch signaling: cell fate control and signal integration in development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Presenilin is required for activity and nuclear access of Notch in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Evidence for a physical interaction between presenilin and Notch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

The Notch1 receptor is cleaved constitutively by a furin-like convertase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Nuclear access and action of notch in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Presenilins: genes for life and death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Amyloid, the presenilins and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

The shortest path from the surface to the nucleus: RBP-J kappa/Su(H) transcription factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Functional conservation of mouse Notch receptor family members

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Motch A and motch B--two mouse Notch homologues coexpressed in a wide variety of tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Jagged: A mammalian ligand that activates notch1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Disruption of the mouse RBP-J kappa gene results in early embryonic death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

"Secretase," Alzheimer amyloid protein precursor secreting enzyme is not sequence-specific

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

A homolog of Drosophila Notch expressed during mammalian development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Notch2: a second mammalian Notch gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55367

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11459941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.161269998

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference