Excess beta-catenin promotes accumulation of transcriptionally active p53. (Q33891005)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10357817%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Excess beta-catenin promotes accumulation of transcriptionally active p53 (English)

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8 December 2019

1 reference

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8 December 2019

A Damalas

1 reference

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8 December 2019

I Simcha

1 reference

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8 December 2019

M Shtutman

1 reference

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8 December 2019

J F Leal

1 reference

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8 December 2019

J Zhurinsky

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8 December 2019

B Geiger

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8 December 2019

M Oren

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8 December 2019

language of work or name

English

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publication date

1 June 1999

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8 December 2019

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8 December 2019

volume

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8 December 2019

issue

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8 December 2019

page(s)

3054-3063

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

8 December 2019

cites work

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The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

5 July 2018

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

5 July 2018

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

5 July 2018

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The complexity of p53 modulation: emerging patterns from divergent signals

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Identification of c-MYC as a target of the APC pathway

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Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

5 July 2018

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Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing

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5 July 2018

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Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3.

5 July 2018

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Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

5 July 2018

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

5 July 2018

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Beta-catenin: a key mediator of Wnt signaling

5 July 2018

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

5 July 2018

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

5 July 2018

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TCF/LEF factor earn their wings

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5 July 2018

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Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Regulation of p53 stability by Mdm2

5 July 2018

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Mdm2 promotes the rapid degradation of p53

5 July 2018

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Beta-catenin as oncogene: the smoking gun.

5 July 2018

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Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

5 July 2018

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

5 July 2018

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

5 July 2018

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

5 July 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

5 July 2018

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p53, the cellular gatekeeper for growth and division

5 July 2018

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p53; from inductive signal to cellular effect

5 July 2018

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5 July 2018

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5 July 2018

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Functional interaction of beta-catenin with the transcription factor LEF-1

5 July 2018

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5 July 2018

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A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

5 July 2018

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5 July 2018

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WAF1, a potential mediator of p53 tumor suppression

5 July 2018

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From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

5 July 2018

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Mediation of c-Myc-induced apoptosis by p53.

5 July 2018

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

5 July 2018

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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

5 July 2018

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Cyclin G is a transcriptional target of the p53 tumor suppressor protein

5 July 2018

1 reference

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Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites

5 July 2018

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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

5 July 2018

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Mapping of the p53 and mdm-2 Interaction Domains

5 July 2018

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BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

5 July 2018

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p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts

5 July 2018

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Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

5 July 2018

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Keeping an old friend under control: regulation of p53 stability

5 July 2018

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E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells

29 October 2018

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Expression of E-cadherin and its relation to the p53 protein status in human breast carcinomas.

29 October 2018

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Cellular adhesion regulates p53 protein levels in primary human keratinocytes.

29 October 2018

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E-cadherin quantitative immunocytochemical assays in breast carcinomas

29 October 2018

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29 October 2018

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Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients.

29 October 2018

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p53 Protein overexpression in colorectal tumors from patients with familial adenomatous polyposis: is it an early or late event?

29 October 2018

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Molecular events including p53 and k-ras alterations in the in vitro progression of a human colorectal adenoma cell line to an adenocarcinoma.

29 October 2018

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Signaling to p53: breaking the MDM2-p53 circuit

29 October 2018

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12 December 2020

Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer

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12 December 2020

An insight into the life of p53: a protein coping with many functions! Review of the 9th p53 Workshop, Crete, May 9-13, 1998

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12 December 2020

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

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12 December 2020

Inhibition of apoptosis during development of colorectal cancer

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12 December 2020

p53 alterations in progenitor lesions of the bronchus, esophagus, oral cavity, and colon

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12 December 2020

In vivo ubiquitination and proteasome-mediated degradation of p53(1)

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12 December 2020

p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features

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12 December 2020

Frequently elevated content of immunochemically defined wild-type p53 protein in colorectal adenomas

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12 December 2020

mdm2 deletion does not alter growth characteristics of p53-deficient embryo fibroblasts

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/18.11.3054

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10357817%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10357817%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

10357817

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10357817%20AND%20SRC:MED&resulttype=core&format=json