Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning (Q33888488)

29 July 2017

title

Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning (English)

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29 July 2017

Celli G

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29 July 2017

LaRochelle WJ

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29 July 2017

Mackem S

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29 July 2017

Sharp R

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29 July 2017

Merlino G

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29 July 2017

language of work or name

English

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publication date

1 March 1998

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

1642-1655

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Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

29 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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Fibroblast growth factor receptor 3 is a negative regulator of bone growth

5 July 2018

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5 July 2018

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Pax-2 controls multiple steps of urogenital development

5 July 2018

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Keratinocyte growth factor is required for hair development but not for wound healing

5 July 2018

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The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary

5 July 2018

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FGF-4 and BMP-2 have opposite effects on limb growth.

5 July 2018

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Structural and functional diversity in the FGF receptor multigene family

5 July 2018

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Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)

5 July 2018

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Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice

5 July 2018

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High-affinity binding sites for related fibroblast growth factor ligands reside within different receptor immunoglobulin-like domains

5 July 2018

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5 July 2018

FGF3 from Xenopus laevis

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Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear

5 July 2018

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FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

5 July 2018

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FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions

5 July 2018

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The ins and outs of fibroblast growth factors

5 July 2018

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Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung.

5 July 2018

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The function of KGF in morphogenesis of epithelium and reepithelialization of wounds

5 July 2018

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FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations

5 July 2018

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FGF-2: apical ectodermal ridge growth signal for chick limb development

5 July 2018

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Fibroblast growth factors induce additional limb development from the flank of chick embryos

5 July 2018

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Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors

5 July 2018

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Requirement of FGF-4 for postimplantation mouse development

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Basic fibroblast growth factor can mediate the early inductive events in renal development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Heparan sulfates mediate the binding of basic fibroblast growth factor to a specific receptor on neural precursor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells

5 July 2018

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Mammalian lung development: interactions in primordium formation and bronchial morphogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Purification and characterization of a newly identified growth factor specific for epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

5 July 2018

1 reference

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Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Characterization of the receptor for keratinocyte growth factor. Evidence for multiple fibroblast growth factor receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

The int-2 proto-oncogene is responsible for induction of the inner ear

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Expression cDNA Cloning of the KGF Receptor by Creation of a Transforming Autocrine Loop

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Developmental expression of two murine fibroblast growth factor receptors, flg and bek

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

5 July 2018

1 reference

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Complexity of FGF receptors: genetic basis for structural diversity and functional specificity

5 July 2018

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A naturally occurring secreted form of fibroblast growth factor (FGF) receptor 1 binds basic FGF in preference over acidic FGF

5 July 2018

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breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170512

Expression of keratinocyte growth factor in embryonic liver of transgenic mice causes changes in epithelial growth and differentiation resulting in polycystic kidneys and other organ malformations.

5 July 2018

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Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family

29 October 2018

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TTF-1 regulates lung epithelial morphogenesis

29 October 2018

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Roles for FGF8 in the induction, initiation, and maintenance of chick limb development

29 October 2018

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Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis

29 October 2018

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Branching morphogenesis of embryonic mouse lung epithelium in mesenchyme-free culture

29 October 2018

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12 December 2020

Mammalian lung development: interactions in formation and morphogenesis of tracheal buds

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12 December 2020

Inhibition of platelet-derived growth factor autocrine growth stimulation by a monoclonal antibody to the human alpha platelet-derived growth factor receptor

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12 December 2020

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

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12 December 2020

Murine FGFR-1 is required for early postimplantation growth and axial organization

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12 December 2020

Transforming growth factor alpha disrupts the normal program of cellular differentiation in the gastric mucosa of transgenic mice

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12 December 2020

Craniofacial syndromes: no such thing as a single gene disease

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12 December 2020

Ectoderm-mesenchyme and mesenchyme-mesenchyme interactions regulate Msx-1 expression and cellular differentiation in the murine limb bud

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Expression of a truncated FGF receptor results in defective lens development in transgenic mice

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Crossing receptor boundaries

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12 December 2020

Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak

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12 December 2020

An essential heparin-binding domain in the fibroblast growth factor receptor kinase

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/17.6.1642

1 reference

29 July 2017

1 reference

29 July 2017

1 reference