Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis (Q33713298)

28 July 2017

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title

Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis (English)

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28 July 2017

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Janeway CA Jr

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28 July 2017

Wong FS

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28 July 2017

Dittel BN

series ordinal

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28 July 2017

publication date

1 June 1999

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28 July 2017

published in

Immunological Reviews

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28 July 2017

volume

169

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28 July 2017

page(s)

93-104

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The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice

28 July 2017

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B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

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Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

21 January 2018

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21 January 2018

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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

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Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

21 January 2018

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Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease

21 January 2018

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A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes

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Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

21 January 2018

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Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

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Peripheral T cell clones from NOD mice specific for GAD65 peptides: lack of islet responsiveness or diabetogenicity

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IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus

21 January 2018

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CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

21 January 2018

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CD4+ beta islet cell-reactive T cell clones that suppress autoimmune diabetes in nonobese diabetic mice

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Molecular Role of TGF-β, Secreted from a New Type of CD4+Suppressor T cell, NY4.2, in the Prevention of Autoimmune IDDM in NOD Mice

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Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

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Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes

21 January 2018

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Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells

21 January 2018

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Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

21 January 2018

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Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

21 January 2018

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

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Cytokines induce the development of functionally heterogeneous T helper cell subsets

21 January 2018

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TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype

21 January 2018

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Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

21 January 2018

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Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

21 January 2018

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Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

21 January 2018

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Mechanisms of beta cell death in diabetes: a minor role for CD95.

21 January 2018

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Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

21 January 2018

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Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts.

21 January 2018

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Beta cell apoptosis in T cell-mediated autoimmune diabetes

21 January 2018

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A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

21 January 2018

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Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

21 January 2018

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Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

21 January 2018

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Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

21 January 2018

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Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma

21 January 2018

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CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice

21 January 2018

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Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis

21 January 2018

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Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice

21 January 2018

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Experimental allergic encephalomyelitis: the balance between encephalitogenic T lymphocytes and demyelinating antibodies determines size and structure of demyelinated lesions.

21 January 2018

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B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice

21 January 2018

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Low avidity recognition of self-antigen by T cells permits escape from central tolerance.

21 January 2018

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Induction of apoptosis and T helper 2 (Th2) responses correlates with peptide affinity for the major histocompatibility complex in self-reactive T cell receptor transgenic mice

21 January 2018

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Mechanisms of recovery from experimental autoimmune encephalomyelitis: T cell deletion and immune deviation in myelin basic protein T cell receptor transgenic mice

21 January 2018

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Fas and Fas ligand: lpr and gld mutations

21 January 2018

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Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions

21 January 2018

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Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01309.X

Oral administration of human insulin to NOD mice generates CD4+ T cells that suppress adoptive transfer of diabetes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01309.X

Protection from insulin dependent diabetes mellitus afforded by insulin antigens in incomplete Freund's adjuvant depends on route of administration

21 January 2018

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The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen

21 January 2018

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The threshold for autoimmune T cell killing is influenced by B7-1

21 January 2018

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Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens

21 January 2018

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A new type of CD4+ suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice

21 January 2018

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The role of Fas in autoimmune diabetes

21 January 2018

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Following a diabetogenic T cell from genesis through pathogenesis

21 January 2018

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High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01309.X

Do B cells drive the diversification of immune responses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01309.X

10.1111/J.1600-065X.1999.TB01309.X

21 January 2018

Identifiers

DOI

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28 July 2017

1 reference