Regulation of GPR54 signaling by GRK2 and {beta}-arrestin (Q33642051)

28 July 2017

title

Regulation of GPR54 signaling by GRK2 and {beta}-arrestin (English)

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28 July 2017

Robert P Millar

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Macarena Pampillo

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28 July 2017

Natasha Camuso

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28 July 2017

Jay E Taylor

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28 July 2017

Jacob M Szereszewski

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28 July 2017

Maryse R Ahow

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28 July 2017

Mateusz Zajac

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28 July 2017

Moshmi Bhattacharya

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28 July 2017

Andy V Babwah

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28 July 2017

publication date

21 October 2009

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28 July 2017

published in

Molecular Endocrinology

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

2060-2074

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Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells.

28 July 2017

cites work

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21 June 2018

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21 June 2018

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Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54.

21 June 2018

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Structure/function analysis of alpha2A-adrenergic receptor interaction with G protein-coupled receptor kinase 2

21 June 2018

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Phosphorylation-independent beta-arrestin translocation and internalization of leukotriene B4 receptors

21 June 2018

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21 June 2018

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21 June 2018

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Agonist-independent internalization of metabotropic glutamate receptor 1a is arrestin- and clathrin-dependent and is suppressed by receptor inverse agonists

21 June 2018

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21 June 2018

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G Protein-coupled receptor kinase 2 regulator of G protein signaling homology domain binds to both metabotropic glutamate receptor 1a and Galphaq to attenuate signaling

21 June 2018

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The GPR54 gene as a regulator of puberty

21 June 2018

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Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54

21 June 2018

1 reference

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The third intracellular loop of alpha 2-adrenergic receptors determines subtype specificity of arrestin interaction

21 June 2018

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21 June 2018

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21 June 2018

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Endogenous G protein-coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells

21 June 2018

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The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors

21 June 2018

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Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2

21 June 2018

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Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Desensitization of G protein-coupled receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Establishment and Characterization of First Trimester Human Trophoblast Cells with Extended Lifespan

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): a finding with therapeutic implications

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Evolved regulation of gonadotropin-releasing hormone receptor cell surface expression

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

The metabotropic glutamate receptor mGluR5 is endocytosed by a clathrin-independent pathway.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Regulation of RGS3 and RGS10 palmitoylation by GnRH.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: agonist-stimulated endocytosis is beta-arrestin1 isoform-specific.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419131

G protein-coupled receptor kinases

30 October 2018

1 reference

12 December 2020

Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice

1 reference

12 December 2020

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

1 reference

12 December 2020

The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane

1 reference

12 December 2020

The rat gonadotropin-releasing hormone receptor internalizes via a beta-arrestin-independent, but dynamin-dependent, pathway: addition of a carboxyl-terminal tail confers beta-arrestin dependency

1 reference

12 December 2020

Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited

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12 December 2020

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2009-0013

1 reference

28 July 2017

1 reference

28 July 2017

1 reference