Structures of kinesin and kinesin-microtubule interactions (Q33536507)

27 July 2017

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title

Structures of kinesin and kinesin-microtubule interactions (English)

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27 July 2017

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27 July 2017

E Mandelkow

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27 July 2017

publication date

1 February 1999

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Current Opinion in Cell Biology

27 July 2017

published in

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27 July 2017

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27 July 2017

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27 July 2017

page(s)

34-44

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Kinesin and dynein superfamily proteins and the mechanism of organelle transport

27 July 2017

cites work

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7 January 2021

Cruising along microtubule highways: how membranes move through the secretory pathway

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7 January 2021

Motor and cargo interactions

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7 January 2021

Motors involved in spindle assembly and chromosome segregation

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7 January 2021

A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.

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7 January 2021

The kinetic cycles of myosin, kinesin, and dynein

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7 January 2021

Molecular motors: the natural economy of kinesin.

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7 January 2021

The structural and mechanochemical cycle of kinesin

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7 January 2021

The movement of kinesin along microtubules

1 reference

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7 January 2021

Leading the procession: new insights into kinesin motors

1 reference

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7 January 2021

Structural variations among the kinesins

1 reference

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7 January 2021

A kinesin medley: biochemical and functional heterogeneity

1 reference

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7 January 2021

Kinesin proteins: a phylum of motors for microtubule-based motility

1 reference

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7 January 2021

The case for a common ancestor: kinesin and myosin motor proteins and G proteins

1 reference

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7 January 2021

Kinesin and myosin: molecular motors with similar engines

1 reference

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7 January 2021

The design plan of kinesin motors

1 reference

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7 January 2021

Motor proteins of the kinesin family. Structures, variations, and nucleotide binding sites

1 reference

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7 January 2021

Nucleotide-dependent angular change in kinesin motor domain bound to tubulin.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Nucleotide-dependent structural changes in dimeric NCD molecules complexed to microtubules.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Three-dimensional structure of a tubulin-motor-protein complex

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Image reconstructions of microtubules decorated with monomeric and dimeric kinesins: comparison with x-ray structure and implications for motility

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Motor domains of kinesin and ncd interact with microtubule protofilaments with the same binding geometry

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

A model for the microtubule-Ncd motor protein complex obtained by cryo-electron microscopy and image analysis

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Three-dimensional structure of functional motor proteins on microtubules

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Nucleotide-dependent conformations of the kinesin dimer interacting with microtubules.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

A model of the microtubule-kinesin complex based on electron cryomicroscopy and X-ray crystallography

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Three-dimensional structure of the kinesin head-microtubule complex

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Crystal structure of the kinesin motor domain reveals a structural similarity to myosin

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Crystal structure of the motor domain of the kinesin-related motor ncd.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Direction determination in the minus-end-directed kinesin motor ncd

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

X-ray structure of motor and neck domains from rat brain kinesin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

The crystal structure of dimeric kinesin and implications for microtubule-dependent motility

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Structure of the alpha beta tubulin dimer by electron crystallography

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

High-resolution model of the microtubule

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Microtubule Interaction Site of the Kinesin Motor

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Proteolytic mapping of kinesin/ncd-microtubule interface: nucleotide-dependent conformational changes in the loops L8 and L12

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Reversal in the direction of movement of a molecular motor

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Determinants of kinesin motor polarity.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Influence of the kinesin neck domain on dimerization and ATPase kinetics

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Demonstration of coiled-coil interactions within the kinesin neck region using synthetic peptides. Implications for motor activity

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7 January 2021

Identification of kinesin neck region as a stable alpha-helical coiled coil and its thermodynamic characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Interaction of monomeric and dimeric kinesin with microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

The coiled-coil helix in the neck of kinesin

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Conformations of kinesin: solution vs. crystal structures and interactions with microtubules

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Role of the kinesin neck region in processive microtubule-based motility

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Switches, latches, and amplifiers: common themes of G proteins and molecular motors

1 reference

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7 January 2021

Deciphering the alphabet of G proteins: the structure of the alpha, beta, gamma heterotrimer

1 reference

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7 January 2021

G protein mechanisms: insights from structural analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Structural studies on myosin II: Communication between distant protein domains

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Recombinant kinesin motor domain binds to beta-tubulin and decorates microtubules with a B surface lattice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

The anatomy of flagellar microtubules: polarity, seam, junctions, and lattice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Re-examination of the Polarity of Microtubules and Sheets Decorated with Kinesin Motor Domain

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Polarity of 2-D and 3-D Maps of Tubulin Sheets and Motor-decorated Sheets

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Microtubule minus ends can be labelled with a phage display antibody specific to alpha-tubulin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Localization of an exchangeable GTP binding site at the plus end of microtubules

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Binding sites on microtubules of kinesin motors of the same or opposite polarity.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Kinesin and ncd bind through a single head to microtubules and compete for a shared MT binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Alternating site mechanism of the kinesin ATPase.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Interaction of mant-adenosine nucleotides and magnesium with kinesin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Pathway of ATP hydrolysis by monomeric and dimeric kinesin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Kinetic mechanism of monomeric non-claret disjunctional protein (Ncd) ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Interacting head mechanism of microtubule-kinesin ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Monomeric kinesin head domains hydrolyze multiple ATP molecules before release from a microtubule

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Characterization of the biophysical and motility properties of kinesin from the fungus Neurospora crassa

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Coupling of kinesin steps to ATP hydrolysis

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Kinesin hydrolyses one ATP per 8-nm step

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

One-headed kinesin derivatives move by a nonprocessive, low-duty ratio mechanism unlike that of two-headed kinesin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Processivity of the motor protein kinesin requires two heads

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Kinetics of force generation by single kinesin molecules activated by laser photolysis of caged ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Direct observation of single kinesin molecules moving along microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

A point mutation in the microtubule binding region of the Ncd motor protein reduces motor velocity.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Nucleotide-dependent movements of the kinesin motor domain predicted by simulated annealing.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Probing the kinesin-microtubule interaction

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https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Movements of truncated kinesin fragments with a short or an artificial flexible neck

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Binding of ncd to Microtubules Induces a Conformational Change near the Junction of the Motor Domain with the Neck

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Importance of a flexible hinge near the motor domain in kinesin-driven motility

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

A marine natural product inhibitor of kinesin motors.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Immunochemical analysis of kinesin light chain function

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Light chain-dependent regulation of Kinesin's interaction with microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

The swinging lever-arm hypothesis of muscle contraction.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Crystal structure of the bacterial cell-division protein FtsZ

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

Interaction of the N-terminal domain of MukB with the bacterial tubulin homologue FtsZ.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980005-2

7 January 2021

10.1016/S0955-0674(99)80005-2

Identifiers

DOI

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27 July 2017

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