Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor (Q30525273)

13 August 2017

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor (English)

1 reference

13 August 2017

Maria Yazdanbakhsh

1 reference

13 August 2017

Alwin J van der Ham

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Thomas Scholzen

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Bart Everts

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Hermelijn H Smits

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Cornelis H Hokke

1 reference

13 August 2017

Edward J Pearce

1 reference

13 August 2017

Leonie Hussaarts

1 reference

13 August 2017

Nicole N Driessen

1 reference

13 August 2017

Moniek H J Meevissen

1 reference

13 August 2017

Gabriele Schramm

1 reference

13 August 2017

Barbara van der Hoeven

1 reference

13 August 2017

Sven Burgdorf

1 reference

13 August 2017

Markus Mohrs

1 reference

13 August 2017

Helmut Haas

1 reference

13 August 2017

language of work or name

English

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publication date

10 September 2012

1 reference

Journal of Experimental Medicine

13 August 2017

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13 August 2017

209

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13 August 2017

1 reference

13 August 2017

1753-67, S1

1 reference

Whole-genome sequence of Schistosoma haematobium

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

Schistosoma mansoni egg glycoproteins and C-type lectins of host immune cells: molecular partners that shape immune responses

20 June 2018

1 reference

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IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity

20 June 2018

1 reference

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Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

20 June 2018

1 reference

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CD11c depletion severely disrupts Th2 induction and development in vivo

20 June 2018

1 reference

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Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation

20 June 2018

1 reference

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The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells

20 June 2018

1 reference

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Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

20 June 2018

1 reference

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Zebrafish RNase T2 genes and the evolution of secretory ribonucleases in animals

20 June 2018

1 reference

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The Schistosoma japonicum genome reveals features of host-parasite interplay

20 June 2018

1 reference

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20 June 2018

1 reference

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Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function

20 June 2018

1 reference

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Uncoupling of induced protein processing from maturation in dendritic cells exposed to a highly antigenic preparation from a helminth parasite

20 June 2018

1 reference

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The mannose receptor mediates dengue virus infection of macrophages

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

Alarming dendritic cells for Th2 induction

20 June 2018

1 reference

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Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

20 June 2018

1 reference

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Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.

20 June 2018

1 reference

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Fungal ribotoxins: molecular dissection of a family of natural killers

20 June 2018

1 reference

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IPSE/alpha-1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core-difucosylated N-glycans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

Pathogen recognition and innate immunity

20 June 2018

1 reference

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A two-step process for cytokine production revealed by IL-4 dual-reporter mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding.

20 June 2018

1 reference

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Delivery into cells: lessons learned from plant and bacterial toxins

20 June 2018

1 reference

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Dendritic-cell control of pathogen-driven T-cell polarization

20 June 2018

1 reference

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Oligolysine-based oligosaccharide clusters: selective recognition and endocytosis by the mannose receptor and dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

The mannose receptor family

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457738

20 June 2018

1 reference

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Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

20 June 2018

1 reference

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Involvement of mannose receptor in cytokine interleukin-1beta (IL-1beta), IL-6, and granulocyte-macrophage colony-stimulating factor responses, but not in chemokine macrophage inflammatory protein 1beta (MIP-1beta), MIP-2, and KC responses, caused b

20 June 2018

1 reference

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

20 June 2018

1 reference

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CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major

20 June 2018

1 reference

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Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

20 June 2018

1 reference

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A mechanism of the irreversible inactivation of bovine pancreatic ribonuclease by diethylpyrocarbonate. A general reaction of diethylpyrocarbonate . A general reaction of diethylpyrocarbonate with proteins

20 June 2018

1 reference

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Inhibition by ricin of protein synthesis in vitro. Ribosomes as the target of the toxin

20 June 2018

1 reference

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Contribution to ligand binding by multiple carbohydrate-recognition domains in the macrophage mannose receptor

20 June 2018

1 reference

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Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.

20 June 2018

1 reference

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21 January 2018

1 reference

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Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

21 January 2018

1 reference

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Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program

21 January 2018

1 reference

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Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111381

Molecular characterization of omega-1: a hepatotoxic ribonuclease from Schistosoma mansoni eggs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111381

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

21 January 2018

1 reference

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Periodate-sensitive immunological cross-reactivity between keyhole limpet haemocyanin (KLH) and serodiagnostic Schistosoma mansoni egg antigens

21 January 2018

1 reference

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The dendritic cell mannose receptor mediates allergen internalization and maturation involving notch 1 signalling

21 January 2018

1 reference

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Structural characterization of glycans on omega-1, a major Schistosoma mansoni egg glycoprotein that drives Th2 responses

21 January 2018

1 reference

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Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

21 January 2018

1 reference

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The mannose receptor mediates the uptake of diverse native allergens by dendritic cells and determines allergen-induced T cell polarization through modulation of IDO activity

21 January 2018

1 reference

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Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanism

21 January 2018

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Specificity of DC-SIGN for mannose- and fucose-containing glycans

21 January 2018

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Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation

21 January 2018

1 reference

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Cytokine-modulated regulation of helper T cell populations.

21 January 2018

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IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni.

21 January 2018

1 reference

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Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants on Schistosoma mansoni egg antigens

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Mitogillin and related fungal ribotoxins

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Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals

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Detection of monoclonal antibodies specific for carbohydrate epitopes using periodate oxidation

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Novel Asn-linked oligosaccharides terminating in GalNAc beta (1-->4)[Fuc alpha (1-->3)]GlcNAc beta (1-->.) are present in recombinant human protein C expressed in human kidney 293 cells

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Identifiers

DOI

10.1084/JEM.20111381

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22966004

1 reference