Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice (Q30523813)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Qingshan Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Eun-Joo Shin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Xuan-Khanh Thi Nguyen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Quan Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Jae-Hyung Bach

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Won-Ki Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Hyoung-Chun Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

publication date

13 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neuroinflammation

5 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3409049/fullTextXML

inferred from PubMed Central ID database lookup

cites work

PKCδ inhibition enhances tyrosine hydroxylase phosphorylation in mice after methamphetamine treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Reactive microgliosis: extracellular micro-calpain and microglia-mediated dopaminergic neurotoxicity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Effects of prodynorphin deletion on striatal dopamine in mice during normal aging and in response to MPTP.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Dynorphin and the pathophysiology of drug addiction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

TNF-alpha knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Role of monoamine transporters in mediating psychostimulant effects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

The basal ganglia: learning new tricks and loving it.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Design-based stereology in neuroscience

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Parkinson's disease: mechanisms and models

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Behavioral phenotyping of mice in pharmacological and toxicological research

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Strain-dependent recovery of open-field behavior and striatal dopamine deficiency in the mouse MPTP model of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Pathophysiology of levodopa-induced dyskinesia: potential for new therapies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Modulation of neurotransmitter release in the basal ganglia of the rat brain by dynorphin peptides.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

The efficiency of systematic sampling in stereology--reconsidered.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Role of dynorphin and enkephalin in the regulation of striatal output pathways and behavior

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Drug-free evaluation of rat models of parkinsonism and nigral grafts using a new automated rotarod test

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Treatment of mice with methamphetamine produces cell loss in the substantia nigra

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Further studies of the role of hyperthermia in methamphetamine neurotoxicity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: in situ hybridization histochemical analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Striatonigral GABA, dynorphin, substance P and neurokinin A modulation of nigrostriatal dopamine release: evidence for direct regulatory mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Endogenous kappa opioid activation mediates stress-induced deficits in learning and memory.

20 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Alterations in GAD67, dynorphin and enkephalin mRNA in striatal output neurons following priming in the 6-OHDA model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Generation of dynorphin knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Prodynorphin gene deficiency potentiates nalbuphine-induced behavioral sensitization and withdrawal syndrome in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Bone morphogenetic protein-7 reduces toxicity induced by high doses of methamphetamine in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

New morphinan derivatives with negligible psychotropic effects attenuate convulsions induced by maximal electroshock in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Potentiation of methamphetamine neurotoxicity by intrastriatal lipopolysaccharide administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Modulation of dopaminergic and glutamatergic brain function: PET studies on parkinsonian rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Computerized morphometric analysis of pathological prion protein deposition in scrapie-infected hamster brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Fluoxetine increases long-lasting neostriatal dopamine depletion after administration of d-methamphetamine and d-amphetamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Alpha-methyltyrosine attenuates and reserpine increases methamphetamine-induced neuronal changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Presence of reactive microglia in monkey substantia nigra years after 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-124

Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Femtomolar concentrations of dynorphins protect rat mesencephalic dopaminergic neurons against inflammatory damage

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Inhibition of lipopolysaccharide-induced nitric oxide and cytokine production by ultralow concentrations of dynorphins in mixed glia cultures

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409049

Rapid and reversible effects of methamphetamine on dopamine transporters

26 November 2018

1 reference

12 December 2020

Selenium deficiency potentiates methamphetamine-induced nigral neuronal loss; comparison with MPTP model

1 reference

12 December 2020

1 reference

12 December 2020

Locus coeruleus lesions potentiate neurotoxic effects of MPTP in dopaminergic neurons of the substantia nigra

1 reference

12 December 2020

Methamphetamine-induced hyperthermia and dopaminergic neurotoxicity in mice: pharmacological profile of protective and nonprotective agents

1 reference

12 December 2020

Identifiers

DOI

10.1186/1742-2094-9-124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 February 2020

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1742-2094-9-124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

22695044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695044%20AND%20SRC:MED&resulttype=core&format=json