Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B. (Q30425800)

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20 January 2020

title

Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B (English)

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20 January 2020

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20 January 2020

Lydia Kutzler

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20 January 2020

Scot R Kimball

series ordinal

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20 January 2020

Ira Tabas

series ordinal

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20 January 2020

publication date

8 January 2012

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20 January 2020

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volume

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issue

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20 January 2020

page(s)

192-200

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Macrophages in the pathogenesis of atherosclerosis

20 January 2020

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20 June 2018

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Epidermal Growth Factor-dependent Regulation of Cdc42 Is Mediated by the Src Tyrosine Kinase

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20 June 2018

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Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation

20 June 2018

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Endotoxin (LPS) stimulates 4E-BP1/PHAS-I phosphorylation in macrophages

20 June 2018

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c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

20 June 2018

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20 June 2018

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Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2

20 June 2018

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20 June 2018

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Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

20 June 2018

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20 June 2018

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20 June 2018

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Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.

20 June 2018

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Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFkappaB activation via Src-dependent blockade of PP2A.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Functional expression of human PP2Ac in yeast permits the identification of novel C-terminal and dominant-negative mutant forms

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22231169

12 December 2020

inferred from PubMed ID database lookup

The Phenotype of Inflammatory Macrophages Is Stimulus Dependent: Implications for the Nature of the Inflammatory Response

1 reference

7 January 2021

Ectopic expression of eIF2Bepsilon in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis

1 reference

7 January 2021

Initiation of protein synthesis in a cell-free system prepared from rat hepatocytes.

1 reference

7 January 2021

Physiological stresses inhibit guanine-nucleotide-exchange factor in Ehrlich cells

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7 January 2021

Identifiers

DOI

10.1038/NCB2408

1 reference

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Dimensions Publication ID

20 January 2020

0 references

1 reference

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20 January 2020

PubMed publication ID

22231169

1 reference

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