Refined solution structure and backbone dynamics of HIV-1 Nef. (Q30176531)

13 August 2017

Refined solution structure and backbone dynamics of HIV-1 Nef. (English)

1 reference

13 August 2017

1 reference

Grzesiek S

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13 August 2017

Bax A

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13 August 2017

Hu JS

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13 August 2017

Kaufman J

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13 August 2017

Palmer I

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13 August 2017

Stahl SJ

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13 August 2017

Tjandra N

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13 August 2017

Wingfield PT

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13 August 2017

1 June 1997

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13 August 2017

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

13 August 2017

1248-1263

1 reference

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Determination of the solution structure of the SH3 domain of human p56 Lck tyrosine kinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The nef gene from a long-term HIV type 1 nonprogressor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Amino acid type determination in the sequential assignment procedure of uniformly 13C/15N-enriched proteins.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Specific suppression of human CD4 surface expression by Nef from the pathogenic simian immunodeficiency virus SIVmac239open

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Stability and proteolytic domains of Nef protein from human immunodeficiency virus (HIV) type 1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The impact of direct refinement against three-bond HN-C alpha H coupling constants on protein structure determination by NMR.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Identification of N-terminal helix capping boxes by means of 13C chemical shifts.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The role of Nef in the replication cycle of the human and simian immunodeficiency viruses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The impact of direct refinement against 13C alpha and 13C beta chemical shifts on protein structure determination by NMR.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulence

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Solution structure of calcium-free calmodulin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Determination of three-dimensional structures of proteins from interproton distance data by hybrid distance geometry-dynamical simulated annealing calculations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Analysis and prediction of the different types of beta-turn in proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Human immunodeficiency virus type 1 negative factor is a transcriptional silencer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labeling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Backbone dynamics of proteins as studied by 15N inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Differential effects of nef on HIV replication: implications for viral pathogenesis in the host

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: applicati

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143732

Left-handed polyproline II helices commonly occur in globular proteins.

20 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Primary structure effects on peptide group hydrogen exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

A possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

MOLMOL: a program for display and analysis of macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Measurement of HN-H alpha J couplings in calcium-free calmodulin using new 2D and 3D water-flip-back methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Use of a water flip-back pulse in the homonuclear NOESY experiment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Flexibility and function in HIV-1 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Proton, carbon-13, nitrogen-15 nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

A simple and sensitive experiment for measurement of JCC couplings between backbone carbonyl and methyl carbons in isotopically enriched proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Four-Dimensional 15N-Separated NOESY of Slowly Tumbling Perdeuterated 15N-Enriched Proteins. Application to HIV-1 Nef

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

A three-dimensional NMR experiment with improved sensitivity for carbonyl-carbonyl J correlation in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Isotope-Filtered 2D HOHAHA Spectroscopy of a Peptide-Protein Complex Using Heteronuclear Hartmann-Hahn Dephasing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060613

Helix stop signals in proteins and peptides: the capping box

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9194185

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9194185

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/PRO.5560060613

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

9194185

1 reference