Spt5 Dmel_CG7626 (Q29814978)

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V460&geneProductId=UniProtKB:Q9V460

1 reference

31 January 2018

chromatin binding

1 reference

8 April 2019

Identification of Regions in the Spt5 Subunit of DRB Sensitivity-inducing Factor (DSIF) That Are Involved in Promoter-proximal Pausing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

protein binding

1 reference

8 April 2019

Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

protein heterodimerization activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

1 reference

8 April 2019

protein-containing complex binding

1 reference

8 April 2019

Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

nuclear exosome (RNase complex)

cell component

1 reference

31 January 2018

The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V460&geneProductId=UniProtKB:Q9V460

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

1 reference

8 April 2019

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

1 reference

8 April 2019

polytene chromosome

1 reference

8 April 2019

Mutations in the transcription elongation factor SPT5 disrupt a reporter for dosage compensation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

polytene chromosome puff

4 references

8 April 2019

Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

8 April 2019

NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

8 April 2019

Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

8 April 2019

High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

polytene chromosome interband

transcription elongation factor complex

1 reference

8 April 2019

Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

DSIF complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

3 references

8 April 2019

8 April 2019

Identification of Regions in the Spt5 Subunit of DRB Sensitivity-inducing Factor (DSIF) That Are Involved in Promoter-proximal Pausing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

FACT complex

1 reference

31 January 2018

Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V460&geneProductId=UniProtKB:Q9V460

negative regulation of transcription by RNA polymerase II

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

4 references

8 April 2019

8 April 2019

Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

IMP

8 April 2019

NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

8 April 2019

Identification of Regions in the Spt5 Subunit of DRB Sensitivity-inducing Factor (DSIF) That Are Involved in Promoter-proximal Pausing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V460&geneProductId=UniProtKB:Q9V460

1 reference

31 January 2018

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

1 reference

8 April 2019

regulation of transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V460&geneProductId=UniProtKB:Q9V460

1 reference

10 September 2018

mRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V460&geneProductId=UniProtKB:Q9V460

1 reference

31 January 2018

dosage compensation

IMP

1 reference

8 April 2019

Mutations in the transcription elongation factor SPT5 disrupt a reporter for dosage compensation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

regulation of DNA-templated transcription, elongation

IMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

1 reference

8 April 2019

positive regulation of DNA-templated transcription, elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

1 reference

8 April 2019

transcription elongation from RNA polymerase II promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

3 references

8 April 2019

8 April 2019

NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V460