Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation (Q28647313)

3 February 2017

title

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation (English)

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3 February 2017

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L. Connell-Crowley

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3 February 2017

J. W. Harper

series ordinal

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3 February 2017

D. W. Goodrich

series ordinal

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3 February 2017

publication date

1 February 1997

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Molecular Biology of the Cell

3 February 2017

published in

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3 February 2017

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3 February 2017

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3 February 2017

page(s)

287–301

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Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit

3 February 2017

cites work

1 reference

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Physical interaction of the retinoblastoma protein with human D cyclins

17 March 2017

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Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

17 March 2017

1 reference

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Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

17 March 2017

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17 March 2017

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Identification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerization

3 June 2018

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Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase

17 March 2017

1 reference

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Identification of G1 kinase activity for cdk6, a novel cyclin D partner

17 March 2017

1 reference

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Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

17 March 2017

1 reference

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Differential regulation of E2F transactivation by cyclin/cdk2 complexes

17 March 2017

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Different roles for cyclins D1 and E in regulation of the G1-to-S transition

17 March 2017

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Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

17 March 2017

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The retinoblastoma protein and cell cycle control

17 March 2017

1 reference

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Growth suppression by p16ink4 requires functional retinoblastoma protein

17 March 2017

1 reference

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Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F

17 March 2017

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Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

17 March 2017

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The retinoblastoma protein is phosphorylated on multiple sites by human cdc2

17 March 2017

1 reference

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Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

17 March 2017

1 reference

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D-type cyclin-dependent kinase activity in mammalian cells

17 March 2017

1 reference

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Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

7 April 2017

1 reference

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

7 April 2017

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Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

7 April 2017

1 reference

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RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila

7 April 2017

1 reference

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Specific enzymatic dephosphorylation of the retinoblastoma protein

3 June 2018

1 reference

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G1 cyclins control the retinoblastoma gene product growth regulation activity via upstream mechanisms

3 June 2018

1 reference

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Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

3 June 2018

1 reference

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Direct transcriptional repression by pRB and its reversal by specific cyclins

3 June 2018

1 reference

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Inhibition of cyclin-dependent kinases by p21

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

The retinoblastoma protein as a fundamental mediator of growth and differentiation signals

3 June 2018

1 reference

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Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

Hyperphosphorylation of the retinoblastoma gene product is determined by domains outside the simian virus 40 large-T-antigen-binding regions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase

3 June 2018

1 reference

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A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product

3 June 2018

1 reference

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Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes

3 June 2018

1 reference

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The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

Activation of human cyclin-dependent kinases in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

The retinoblastoma protein and the regulation of cell cycling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

E2F-induced S phase requires cyclin E.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

In vitro phosphorylation of the tumor suppressor gene RB protein by mitosis-specific histone H1 kinase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=276080

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

27 November 2018

1 reference

12 December 2020

Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product

1 reference

12 December 2020

Regions controlling hyperphosphorylation and conformation of the retinoblastoma gene product are independent of domains required for transcriptional repression

1 reference

12 December 2020

Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein

1 reference

12 December 2020

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.8.2.287

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1 reference

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