Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1 (Q28645598)

3 February 2017

title

Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1 (English)

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3 February 2017

S. Tom

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3 February 2017

L. A. Henricksen

series ordinal

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3 February 2017

R. A. Bambara

series ordinal

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3 February 2017

language of work or name

English

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publication date

7 April 2000

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Journal of Biological Chemistry

3 February 2017

published in

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3 February 2017

volume

275

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3 February 2017

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3 February 2017

page(s)

10498–10505

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Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair

3 February 2017

cites work

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Enzymatic completion of mammalian lagging-strand DNA replication

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Involvement of flap endonuclease 1 in base excision DNA repair.

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DNA structural elements required for FEN-1 binding

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Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

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Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA.

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A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

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Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins

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The crystal structure of flap endonuclease-1 from Methanococcus jannaschii

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Flexible loops and helical arches

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Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

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Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

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Properties of DNA polymerases delta and epsilon, and their roles in eukaryotic DNA replication

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p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex

21 January 2018

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Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen

21 January 2018

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Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1.

21 January 2018

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21.

21 January 2018

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The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21

21 January 2018

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Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

21 January 2018

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Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA.

21 January 2018

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Effect of flap modifications on human FEN1 cleavage

21 January 2018

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Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex

21 January 2018

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Calf RTH-1 nuclease can remove the initiator RNAs of Okazaki fragments by endonuclease activity

21 January 2018

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Mechanism of tracking and cleavage of adduct-damaged DNA substrates by the mammalian 5'- to 3'-exonuclease/endonuclease RAD2 homologue 1 or flap endonuclease 1.

21 January 2018

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A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair

21 January 2018

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A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.

21 January 2018

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Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

21 January 2018

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Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

21 January 2018

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Multiprotein reactions in mammalian DNA replication

21 January 2018

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Conditional lethality of null mutations in RTH1 that encodes the yeast counterpart of a mammalian 5'- to 3'-exonuclease required for lagging strand DNA synthesis in reconstituted systems

21 January 2018

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Role of calf RTH-1 nuclease in removal of 5'-ribonucleotides during Okazaki fragment processing

21 January 2018

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Human RAD2 homolog 1 5'- to 3'-exo/endonuclease can efficiently excise a displaced DNA fragment containing a 5'-terminal abasic lesion by endonuclease activity

21 January 2018

1 reference

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Two Pathways for Base Excision Repair in Mammalian Cells

21 January 2018

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Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.275.14.10498

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