Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells (Q28592033)

31 January 2017

title

Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells (English)

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Mismatch repair endonuclease PMS2

31 January 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

A. Baross-Francis

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31 January 2017

N. Makhani

series ordinal

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31 January 2017

R. M. Liskay

series ordinal

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31 January 2017

F. R. Jirik

series ordinal

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31 January 2017

language of work or name

English

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publication date

1 February 2001

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

619–625

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A novel lacI transgenic mutation-detection system and its application to establish baseline mutation frequencies in the scid mouse

31 January 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Pten is essential for embryonic development and tumour suppression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Mutational spectra: from model systems to cancer-related genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations

21 January 2018

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The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Mouse models for colorectal cancer

21 January 2018

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APC mutations in colorectal tumors with mismatch repair deficiency

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A.

21 January 2018

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Lessons from hereditary colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

21 January 2018

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The use of transgenic mice for short-term, in vivo mutagenicity testing

21 January 2018

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Mismatch repair: mechanisms and relationship to cancer susceptibility

21 January 2018

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Eukaryotic DNA mismatch repair

21 January 2018

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MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability

21 January 2018

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Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Recognition of DNA alterations by the mismatch repair system

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2

21 January 2018

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Alternative genetic pathways in colorectal carcinogenesis.

21 January 2018

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Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

21 January 2018

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MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Different mutator phenotypes in Mlh1- versus Pms2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

Eukaryotic mismatch repair: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

7 January 2021

Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

7 January 2021

DNA mismatch repair and cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

7 January 2021

MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

7 January 2021

DNA mismatch repair and colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

7 January 2021

Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

7 January 2021

Analysis of yeast pms1, msh2, and mlh1 mutators points to differences in mismatch correction efficiencies between prokaryotic and eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204138

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204138

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Dimensions Publication ID

31 January 2017

1018423308

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1 reference