A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2 (Q28588691)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906133%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2 (English)

2 references

PubMed

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906133%20AND%20SRC:MED&resulttype=core&format=json

Transformed mouse 3T3 cell double minute 2

8 November 2019

main subject

1 reference

Mdm2, transformed 3T3 cell double minute p53 binding protein

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906133%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

M T Boyd

1 reference

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8 November 2019

D S Haines

series ordinal

1 reference

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8 November 2019

language of work or name

English

0 references

publication date

1 October 2000

1 reference

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Journal of Biological Chemistry

8 November 2019

published in

2 references

PubMed

31 January 2017

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8 November 2019

volume

275

2 references

PubMed

31 January 2017

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8 November 2019

2 references

31 January 2017

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8 November 2019

page(s)

31883-31890

1 reference

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Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

8 November 2019

cites work

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Mutations in the p53 gene occur in diverse human tumour types

21 January 2018

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Tumor surveillance via the ARF-p53 pathway.

21 January 2018

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Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

21 January 2018

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Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

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The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

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The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

21 January 2018

1 reference

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

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Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

21 January 2018

1 reference

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Mapping of the p53 and mdm-2 Interaction Domains

21 January 2018

1 reference

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

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Regulation of p53 stability by Mdm2

21 January 2018

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mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

21 January 2018

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Interaction between the retinoblastoma protein and the oncoprotein MDM2

21 January 2018

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

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The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.

21 January 2018

1 reference

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Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

21 January 2018

1 reference

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Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

21 January 2018

1 reference

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Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

21 January 2018

1 reference

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p53-independent role of MDM2 in TGF-beta1 resistance

21 January 2018

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pBD7, a novel cell-free expression vector with efficient translation initiation signal

21 January 2018

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Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

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A novel genetic system to detect protein-protein interactions

21 January 2018

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Associations among PH and SH3 domain-containing proteins and Rho-type GTPases in Yeast

21 January 2018

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Yeast src homology region 3 domain-binding proteins involved in bud formation

21 January 2018

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Functions of the MDM2 oncoprotein

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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Identification of a ten-amino acid proline-rich SH3 binding site

21 January 2018

1 reference

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p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

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Repression of p53-mediated transcription by MDM2: a dual mechanism

21 January 2018

1 reference

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Role of small G proteins in yeast cell polarization and wall biosynthesis

21 January 2018

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Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

21 January 2018

1 reference

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Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

1 reference

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Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

21 January 2018

1 reference

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Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

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The role of p53 in tumour suppression: lessons from mouse models

21 January 2018

1 reference

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MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M004252200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906133%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906133%20AND%20SRC:MED&resulttype=core&format=json