Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors (Q28584983)

31 January 2017

title

Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors (English)

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G protein-coupled receptor

31 January 2017

main subject

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based on heuristic

inferred from title

Protein phosphatase 1, regulatory subunit 9B

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G protein-coupled receptor kinase 2

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Adrenergic receptor, alpha 2a

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Arrestin 3, retinal

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Adrenergic receptor, alpha 2b

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Arrestin, beta 2

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Paul Greengard

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31 January 2017

Robert J. Lefkowitz

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31 January 2017

Qin Wang

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31 January 2017

Jiali Zhao

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31 January 2017

Ashley E. Brady

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31 January 2017

Jian Feng

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31 January 2017

Patrick B. Allen

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31 January 2017

Lee E. Limbird

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31 January 2017

language of work or name

English

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publication date

25 June 2004

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31 January 2017

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31 January 2017

volume

304

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31 January 2017

issue

5679

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31 January 2017

page(s)

1940–1944

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beta-Arrestin: a protein that regulates beta-adrenergic receptor function

31 January 2017

cites work

1 reference

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Retinal S antigen identified as the 48K protein regulating light-dependent phosphodiesterase in rods

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New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

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Regulated interactions of the alpha 2A adrenergic receptor with spinophilin, 14-3-3zeta, and arrestin 3.

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11 October 2022

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The third intracellular loop of alpha 2-adrenergic receptors determines subtype specificity of arrestin interaction

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Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein

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Stimulation of mitogen-activated protein kinase by G protein-coupled alpha(2)-adrenergic receptors does not require agonist-elicited endocytosis

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Spinophilin regulates the formation and function of dendritic spines

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A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types

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Arresting developments in heptahelical receptor signaling and regulation

1 reference

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Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

1 reference

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Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo

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The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification

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11 October 2022

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Interaction of arrestins with intracellular domains of muscarinic and alpha2-adrenergic receptors.

1 reference

11 October 2022

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Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Enhanced morphine analgesia in mice lacking beta-arrestin 2

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098274

Identifiers

DOI

10.1126/SCIENCE.1098274

1 reference

31 January 2017

0 references

1 reference