Ink4a/Arf expression is a biomarker of aging (Q28570483)

31 January 2017

title

Ink4a/Arf expression is a biomarker of aging (English)

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response to caloric restriction

31 January 2017

0 references

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0061771

author name string

Janakiraman Krishnamurthy

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31 January 2017

Chad Torrice

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31 January 2017

Matthew R. Ramsey

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31 January 2017

Grigoriy I. Kovalev

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31 January 2017

Khalid Al-Regaiey

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31 January 2017

Lishan Su

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31 January 2017

Norman E. Sharpless

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31 January 2017

language of work or name

English

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publication date

1 November 2004

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Journal of Clinical Investigation

31 January 2017

published in

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31 January 2017

volume

114

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31 January 2017

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31 January 2017

page(s)

1299–1307

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

31 January 2017

cites work

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Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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3 June 2018

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3 June 2018

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3 June 2018

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Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

27 November 2018

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Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney

27 November 2018

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Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells

27 November 2018

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Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening.

27 November 2018

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27 November 2018

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Immunohistochemical expression of p53, p21/waf1, rb, p16, cyclin D1, p27, Ki67, cyclin A, cyclin B1, bcl2, bax and bak proteins and apoptotic index in normal thymus

27 November 2018

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27 November 2018

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Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Aged T cells are hyporesponsive to costimulation mediated by CD28.

27 November 2018

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Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy

27 November 2018

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12 December 2020

Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure

1 reference

12 December 2020

Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues

1 reference

12 December 2020

Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2

1 reference

12 December 2020

Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues

1 reference

12 December 2020

Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI22475

1 reference

1 reference

1 reference

1 reference