Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis (Q28508088)

24 January 2017

title

Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis (English)

1 reference

Beta-transducin repeat containing protein

24 January 2017

main subject

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GOA release 2020-03-11

author

Daniele Guardavaccaro

object named as

Daniele Guardavaccaro

0 references

Yasusei Kudo

0 references

Michele Pagano

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Lili Yamasaki

1 reference

24 January 2017

Ryo Koyama-Nasu

1 reference

24 January 2017

Roderick Bronson

1 reference

24 January 2017

author name string

Patricia G. Santamaria

series ordinal

1 reference

24 January 2017

Esther Latres

series ordinal

1 reference

24 January 2017

language of work or name

English

0 references

publication date

1 September 2004

1 reference

Molecular and Cellular Biology

24 January 2017

published in

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24 January 2017

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24 January 2017

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24 January 2017

page(s)

8184–8194

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The SCF ubiquitin ligase: insights into a molecular machine

24 January 2017

cites work

1 reference

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19 March 2017

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M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

19 March 2017

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19 March 2017

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Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

19 March 2017

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Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

19 March 2017

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Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

19 March 2017

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19 March 2017

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ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase

19 March 2017

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Role of the F-box protein Skp2 in lymphomagenesis

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta

19 March 2017

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Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha

19 March 2017

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19 March 2017

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

19 March 2017

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

19 March 2017

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19 March 2017

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

19 March 2017

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19 March 2017

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A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

19 March 2017

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19 March 2017

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19 March 2017

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

7 April 2017

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

19 March 2017

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A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

19 March 2017

1 reference

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Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1.

19 March 2017

1 reference

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Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase

29 September 2017

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Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors

29 September 2017

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NF-kappaB in cancer: a marked target

29 September 2017

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Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epithelium

29 September 2017

1 reference

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Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland

29 September 2017

1 reference

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Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha

29 September 2017

1 reference

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Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1.

29 September 2017

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How the cyclin became a cyclin: regulated proteolysis in the cell cycle

29 September 2017

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Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515055

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

29 September 2017

1 reference

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Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

29 September 2017

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

29 September 2017

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Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats

29 September 2017

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Association of cdk2 Kinase with the Transcription Factor E2F During S Phase

29 September 2017

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Emi1 proteolysis: how SCF(beta-Trcp1) helps to activate the anaphase-promoting complex.

29 September 2017

1 reference

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Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

27 November 2018

1 reference

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The inhibitory effects of transforming growth factor beta1 on breast cancer cell proliferation are mediated through regulation of aberrant nuclear factor-kappaB/Rel expression.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515055

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515055

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=515055

Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

27 November 2018

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12 December 2020

Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

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12 December 2020

Dynamic expression and activity of NF-kappaB during post-natal mammary gland morphogenesis

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12 December 2020

MMTV-Fgf8 transgenic mice develop mammary and salivary gland neoplasia and ovarian stromal hyperplasia

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12 December 2020

10.1128/MCB.24.18.8184-8194.2004

Identifiers

DOI

1 reference

24 January 2017

0 references

1 reference