AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching (Q28366125)

object named as

M C Nussenzweig

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author name string

S Petersen

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R Casellas

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B Reina-San-Martin

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H T Chen

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M J Difilippantonio

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P C Wilson

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L Hanitsch

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A Celeste

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M Muramatsu

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D R Pilch

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C Redon

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T Ried

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W M Bonner

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T Honjo

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A Nussenzweig

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

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language of work or name

English

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publication date

6 December 2001

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published in

Nature

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volume

414

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issue

6864

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page(s)

660-5

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Megabase chromatin domains involved in DNA double-strand breaks in vivo

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Rad51 expression and localization in B cells carrying out class switch recombination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Linking class-switch recombination with somatic hypermutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

DNA sequences at immunoglobulin switch region recombination sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Ku80 is required for immunoglobulin isotype switching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Directed Ig class switch recombination in activated murine B cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729367

Contribution of Receptor Editing to the Antibody Repertoire

27 November 2018

2 references

PubMed

https://pubmed.ncbi.nlm.nih.gov/11740565

12 December 2020

inferred from PubMed ID database lookup

Crossref

https://api.crossref.org/works/10.1038%2F414660A

7 January 2021

inferred from DOI database lookup

Origin of Antibody Variation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11740565

12 December 2020

inferred from PubMed ID database lookup

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11740565

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/414660A

1 reference

Dimensions Publication ID

1002710847

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Fatcat ID

release_p7darp7ce5afvj5hs5vy5d2xne

0 references

1 reference

1 reference

PubMed publication ID

11740565

1 reference